进餐时间和睡眠持续时间与肥胖发生率的关系：一项前瞻性队列研究。

Associations of meal timing and sleep duration with incidence of obesity: a prospective cohort study.

机构信息

Department of Nutritional Science and Food Management, Ewha Womans University, Seoul 03760, Republic of Korea; Division of Population Health Research, Department of Precision Medicine, Korea National Institute of Health, Korea Disease Control and Prevention Agency, Chungcheongbuk-do 28160, Republic of Korea.

Division of Population Health Research, Department of Precision Medicine, Korea National Institute of Health, Korea Disease Control and Prevention Agency, Chungcheongbuk-do 28160, Republic of Korea.

出版信息

J Nutr Health Aging. 2024 Jun;28(6):100220. doi: 10.1016/j.jnha.2024.100220. Epub 2024 Apr 2.

DOI:10.1016/j.jnha.2024.100220

PMID:38564828

Abstract

OBJECTIVES

Late mealtime and short sleep are known to be associated with obesity risk due to a misaligned circadian rhythm. This study aimed to investigate the relationship between obesity and mealtime and sleep duration using the Korean Genome and Epidemiology Study (KoGES) data.

DESIGN

Longitudinally prospective cohort study.

SETTING

Population-based.

PARTICIPANTS

KoGES analysed data from 9,474 Korean adults with an average age of 54- years old at baseline.

MEASUREMENTS

Meal timing was defined as the eating occasions of the day reported by the participant eating a 24-h dietary recall method. Sleep duration was categorized as <6, 6-7, 7-8, and ≥8 h. The Cox proportional hazard model was used to calculate hazard ratios (HRs) and 95% confidence intervals (CIs) for incident obesity according to meal timing, sleep duration, and nightly fasting duration.

RESULTS

During a mean follow-up of 3.5 years, 826 participants developed obesity. In the multivariable-adjusted analysis, midnight snack eating (HR, 1.20; 95% CI, 1.02-1.41) and higher energy intake from midnight snacks (HR, 1.26; 95% CI, 1.06-1.49) were associated with a higher risk of obesity. Sleeping 8 h or more (HR, 0.67; 95% CI, 0.53-0.85) was associated with a lower risk of obesity.

CONCLUSIONS

Our findings highlight the importance of meal and sleep times and suggest that healthy eating habits related to the time of day.

摘要

目的

由于昼夜节律失调，晚餐时间晚和睡眠不足与肥胖风险有关。本研究旨在使用韩国基因组与流行病学研究（KoGES）的数据调查肥胖与用餐时间和睡眠时间的关系。

设计

纵向前瞻性队列研究。

设置

基于人群。

参与者

KoGES 分析了来自 9474 名韩国成年人的数据，这些成年人在基线时的平均年龄为 54 岁。

测量

用餐时间是通过参与者根据 24 小时膳食回顾法报告的一天中的用餐次数来定义的。睡眠时间分为<6、6-7、7-8 和≥8 小时。使用 Cox 比例风险模型计算根据用餐时间、睡眠时间和夜间禁食时间计算肥胖发生率的风险比（HR）和 95%置信区间（CI）。

结果

在平均 3.5 年的随访期间，826 名参与者发生了肥胖。在多变量调整分析中，吃夜宵（HR，1.20；95%CI，1.02-1.41）和夜宵摄入的能量较高（HR，1.26；95%CI，1.06-1.49）与肥胖风险增加相关。睡 8 小时或更长时间（HR，0.67；95%CI，0.53-0.85）与肥胖风险降低相关。