Institute of Sports and Preventive Medicine, Saarland University, D-66123, Saarbrücken, Germany.
Institute of Sports and Sports Science, Karlsruhe Institute of Technology, D-76131, Karlsruhe, Germany.
BMC Public Health. 2024 Apr 6;24(1):970. doi: 10.1186/s12889-024-18448-3.
To examine the longitudinal associations between fitness and metabolic syndrome (MetS) in community-dwelling adults over 29 years of follow-up.
Ongoing, population-based cohort study of adults aged ≥ 33 years at baseline residing in the city of Bad Schönborn, Germany.
The sample comprised 89 persons (41 females; mean age 40.1 years at baseline) who participated at baseline (in the year 1992) and 29-years follow-up (in the year 2021). Fitness (predictor variable) was assessed using 15 standardized and validated tests that measured strength, gross motor coordination, mobility/ flexibility and cardiorespiratory fitness/ endurance, and a z-transformed fitness score was calculated for analysis. MetS (outcome of interest) was assessed through five criteria related to waist circumference, blood glucose, HDL cholesterol, triglycerides, and blood pressure, and a sum score was created for analysis. We ran partial correlations to examine the association between fitness score at baseline and MetS score at 29-years follow-up, adjusted for age, sex, socio-economic status, smoking status, sleep quality, and physical activity engagement in minutes/ week.
A higher fitness score at baseline was significantly associated with a lower MetS score indicative of better metabolic health at 29-years follow-up (r=-0.29; p = 0.011). These associations were present in participants aged ≤ 40 years (r=-0.33; p = 0.025) as well as those aged > 40 years (r=-0.43; p = 0.045).
Fitness may be a predictor of longitudinal metabolic health, and potentially also mediates previously reported longitudinal associations between physical activity and metabolic health. More research is needed to confirm these observations, and to also explore underlying mechanisms.
在 29 年的随访中，研究社区成年人的体能与代谢综合征（MetS）之间的纵向关联。
这是一项对居住在德国巴特施恩伯尔尼市的成年人进行的基于人群的纵向队列研究。
该样本包括 89 人（41 名女性；基线时的平均年龄为 40.1 岁），他们参加了基线（1992 年）和 29 年随访（2021 年）。使用 15 项标准化和验证过的测试来评估体能（预测变量），这些测试测量了力量、大运动协调性、移动/灵活性和心肺适能/耐力，并计算了一个 z 转换后的体能得分进行分析。代谢综合征（感兴趣的结果）通过与腰围、血糖、高密度脂蛋白胆固醇、甘油三酯和血压相关的五个标准进行评估，并为分析创建了一个总分。我们进行偏相关分析，以检查基线时的体能得分与 29 年随访时的代谢综合征得分之间的关联，调整了年龄、性别、社会经济地位、吸烟状况、睡眠质量和每周运动分钟数。
基线时较高的体能得分与 29 年随访时较低的代谢综合征得分显著相关，表明代谢健康状况更好（r=-0.29；p=0.011）。这些关联在年龄≤40 岁的参与者（r=-0.33；p=0.025）和年龄>40 岁的参与者（r=-0.43；p=0.045）中均存在。
体能可能是纵向代谢健康的预测因素，并且可能也介导了先前报告的体力活动与代谢健康之间的纵向关联。需要更多的研究来证实这些观察结果，并探索潜在的机制。
