Safai Zadeh Ehsan, Görg Mathis, Görg Christian, Prosch Helmut, Trenker Corinna, Westhoff Christina Carolin, Dietrich Christoph F, Raab Nils, Alhyari Amjad, Huber Katharina, Pochepnia Svitlana, Weber Michael, Findeisen Hajo
Department of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, Wien, Austria.
Interdisciplinary Centre of Ultrasound Diagnostics, Gastroenterology, Endocrinology, Metabolism and Clinical Infectiology, University Hospital of Giessen and Marburg Campus Marburg, Marburg, Germany.
Ultraschall Med. 2025 Feb;46(1):66-72. doi: 10.1055/a-2282-2353. Epub 2024 Apr 8.
To evaluate the diagnostic yield of contrast-enhanced ultrasound (CEUS)-guided biopsy of retroperitoneal masses (RMs).
Between 2006 and 2023, 87 patients presented at our US center for biopsy of an RM. In all biopsies, CEUS was performed prior to the intervention. The technical success rate of biopsy, the presence of diagnostic tissue in solid tumor biopsy samples, the accuracy of the biopsy and the occurrence of post-interventional complications were evaluated.
A US-guided biopsy could be conducted in 84/87 cases (96.6%). In 3/87 cases (3.4%), US-guided biopsy was impossible because the planned needle path was obstructed by vital structures. Of 84 lesions, 80 (95.2%) were solid lesions, and 4 (4.8%) were lesions containing fluid. In all solid tumors, 80/80 (100%), diagnostic vital tissue was successfully obtained. CEUS-guided biopsy showed a sensitivity of 93.2%, a specificity of 100%, a positive predictive value of 100%, a negative predictive value of 72.2%, and a diagnostic accuracy of 94.2% for the differentiation between malignant and benign RMs. In one of the 84 cases (1.2%), there was a complication of postinterventional abdominal pain.
Percutaneous CEUS-guided biopsy is a safe procedure with a high diagnostic yield and a low complication rate.
评估超声造影（CEUS）引导下对腹膜后肿块（RM）进行活检的诊断效能。
2006年至2023年期间，87例患者到我们的超声中心进行RM活检。在所有活检中，干预前均进行了CEUS检查。评估活检的技术成功率、实体瘤活检样本中诊断性组织的存在情况、活检的准确性以及干预后并发症的发生情况。
84/87例（96.6%）可进行超声引导下活检。3/87例（3.4%）因计划的穿刺路径被重要结构阻挡而无法进行超声引导下活检。84个病灶中，80个（95.2%）为实性病灶，4个（4.8%）为含液性病灶。在所有实体瘤中，80/80（100%）成功获取了诊断性重要组织。CEUS引导下活检对恶性和良性RM鉴别的敏感性为93.2%，特异性为100%，阳性预测值为100%，阴性预测值为72.2%，诊断准确性为94.2%。84例中有1例（1.2%）出现干预后腹痛并发症。
经皮CEUS引导下活检是一种安全的检查方法，诊断效能高，并发症发生率低。
