Puri Smriti, Nayyar Rohit, Chaturvedi Harit Kumar, Thatai Atul, Agarwal Shweta, Malik Akshat
Department of Surgical Oncology, Max Super Speciality Hospital, 1 2, Press Enclave Marg, Saket Institutional Area, Saket, New Delhi, Delhi 110017 India.
Max Institute of Cancer Care, Max Super Speciality Hospital, 1 2, Press Enclave Marg, Saket Institutional Area, Saket, New Delhi, Delhi 110017 India.
J Maxillofac Oral Surg. 2024 Apr;23(2):316-319. doi: 10.1007/s12663-023-02004-4. Epub 2023 Nov 24.
Giant cell lesions of orofacial region although rare in presentation, have diagnostic and treatment challenges due to overlapping clinical, radiological, and histopathological signs.
We happened to come across a case, which presented to us with an aggressive jaw lesion of nonodontogenic origin, mimicking a malignancy and putting us in a conundrum with regard to work up and treatment. The sequential work up not only helped us reach a definitive diagnosis but also led us the draw algorithms for diagnosis of Giant cell lesions and management of Central giant cell granuloma.
Meticulous planning along with molecular studies helps in better delineating one giant cell lesion from other.
口腔颌面部巨细胞病变虽然临床表现罕见,但由于临床、影像学和组织病理学表现重叠,在诊断和治疗方面存在挑战。
我们偶然遇到一个病例,该病例表现为起源于非牙源性的侵袭性颌骨病变,类似恶性肿瘤,这让我们在检查和治疗方面陷入了困境。连续的检查不仅帮助我们做出了明确的诊断,还引导我们绘制了巨细胞病变的诊断算法和中央巨细胞肉芽肿的治疗方案。
精心规划以及分子研究有助于更好地鉴别不同的巨细胞病变。