Wei Gui-Xia, Zhou Yu-Wen, Li Zhi-Ping, Qiu Meng
Department of Abdominal Cancer, Cancer Center, West China Hospital of Sichuan University, Chengdu, China.
Department of Colorectal Cancer Center, West China Hospital of Sichuan University, Chengdu, China.
Heliyon. 2024 Apr 6;10(7):e29249. doi: 10.1016/j.heliyon.2024.e29249. eCollection 2024 Apr 15.
Peritoneal carcinomatosis (PC) is a type of secondary cancer which is not sensitive to conventional intravenous chemotherapy. Treatment strategies for PC are usually palliative rather than curative. Recently, artificial intelligence (AI) has been widely used in the medical field, making the early diagnosis, individualized treatment, and accurate prognostic evaluation of various cancers, including mediastinal malignancies, colorectal cancer, lung cancer more feasible. As a branch of computer science, AI specializes in image recognition, speech recognition, automatic large-scale data extraction and output. AI technologies have also made breakthrough progress in the field of peritoneal carcinomatosis (PC) based on its powerful learning capacity and efficient computational power. AI has been successfully applied in various approaches in PC diagnosis, including imaging, blood tests, proteomics, and pathological diagnosis. Due to the automatic extraction function of the convolutional neural network and the learning model based on machine learning algorithms, AI-assisted diagnosis types are associated with a higher accuracy rate compared to conventional diagnosis methods. In addition, AI is also used in the treatment of peritoneal cancer, including surgical resection, intraperitoneal chemotherapy, systemic chemotherapy, which significantly improves the survival of patients with PC. In particular, the recurrence prediction and emotion evaluation of PC patients are also combined with AI technology, further improving the quality of life of patients. Here we have comprehensively reviewed and summarized the latest developments in the application of AI in PC, helping oncologists to comprehensively diagnose PC and provide more precise treatment strategies for patients with PC.
腹膜癌病(PC)是一种对传统静脉化疗不敏感的继发性癌症。PC的治疗策略通常是姑息性的而非治愈性的。近年来,人工智能(AI)在医学领域得到广泛应用,使得包括纵隔恶性肿瘤、结直肠癌、肺癌在内的各种癌症的早期诊断、个体化治疗及准确的预后评估变得更加可行。作为计算机科学的一个分支,AI专门从事图像识别、语音识别、大规模数据自动提取与输出。基于其强大的学习能力和高效的计算能力,AI技术在腹膜癌病(PC)领域也取得了突破性进展。AI已成功应用于PC诊断的各种方法中,包括影像学、血液检测、蛋白质组学及病理诊断。由于卷积神经网络的自动提取功能以及基于机器学习算法的学习模型,与传统诊断方法相比,AI辅助诊断类型具有更高的准确率。此外,AI还用于腹膜癌的治疗,包括手术切除、腹腔内化疗、全身化疗,这显著提高了PC患者的生存率。特别是,PC患者的复发预测和情绪评估也与AI技术相结合,进一步提高了患者的生活质量。在此,我们全面回顾并总结了AI在PC应用中的最新进展,帮助肿瘤学家全面诊断PC,并为PC患者提供更精确的治疗策略。