琥珀酸生产的进展：增强CO固定以实现碳封存效益。
Advances in succinic acid production: the enhancement of CO fixation for the carbon sequestration benefits.
作者信息
Lin Fanzhen, Li Wenwei, Wang Dan, Hu Ge, Qin Zhao, Xia Xue, Hu Lin, Liu Xuemei, Luo Ruoshi
机构信息
Department of Chemical Engineering, School of Chemistry and Chemical Engineering, Chongqing University, Chongqing, China.
出版信息
Front Bioeng Biotechnol. 2024 Mar 28;12:1392414. doi: 10.3389/fbioe.2024.1392414. eCollection 2024.
Succinic acid (SA), one of the 12 top platform chemicals produced from biomass, is a precursor of various high value-added derivatives. Specially, 1 mol CO is assimilated in 1 mol SA biosynthetic route under anaerobic conditions, which helps to achieve carbon reduction goals. In this review, methods for enhanced CO fixation in SA production and utilization of waste biomass for SA production are reviewed. Bioelectrochemical and bioreactor coupling systems constructed with off-gas reutilization to capture CO more efficiently were highlighted. In addition, the techno-economic analysis and carbon sequestration benefits for the synthesis of bio-based SA from CO and waste biomass are analyzed. Finally, a droplet microfluidics-based high-throughput screening technique applied to the future bioproduction of SA is proposed as a promising approach.
琥珀酸（SA）是由生物质生产的12种顶级平台化学品之一，是各种高附加值衍生物的前体。特别地，在厌氧条件下，1摩尔一氧化碳在1摩尔SA生物合成途径中被同化，这有助于实现碳减排目标。在本综述中，对提高SA生产中一氧化碳固定的方法以及利用废弃生物质生产SA进行了综述。重点介绍了通过废气再利用构建的生物电化学和生物反应器耦合系统，以更有效地捕获一氧化碳。此外，还分析了由一氧化碳和废弃生物质合成生物基SA的技术经济分析和碳封存效益。最后，提出了一种基于液滴微流控的高通量筛选技术，作为未来SA生物生产的一种有前景的方法。
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