Chaisuksant Seksan, Suwannatat Panupong, Sawanyawisuth Kittisak
Khon Kaen Hospital.
Department of Medicine, Khon Kaen University.
Multidiscip Respir Med. 2024 Apr 12;19(1):951. doi: 10.5826/mrm.2024.951.
Chronic obstructive airway disease (COPD) has been found to be associated with depression. An overlap of COPD and depression may cause poor quality of life and an increase in mortality. A meta-analysis found that the prevalence and risk factors of depression in patients with COPD have high heterogeneity and are limited in tertiary care hospital outpatient settings. This study thus aimed to evaluate the prevalence and risk -factors of depression in patients with COPD using personal data in a tertiary care hospital outpatient setting.
This cross-sectional study included adult patients who were diagnosed with COPD according to the GOLD guidelines, had stable functional status within the past 4 weeks with the same treatment regimen, and had no history of other serious medical or surgical illness. A diagnosis of depression was made according to a score of 11 or higher on the hospital anxiety and depression scale (HADS). The prevalence and predictors of depression were then computed.
The study enrolled and evaluated 150 patients with COPD, out of which 6 (4%) had depression. While the predictive model for depression comprised two factors, only severity of COPD was independently associated with depression. The adjusted odds ratio of severity of COPD was 5.20 (95% confidence interval of 1.75, 15.42; p = 0.003).
The prevalence of depression in patients with COPD in a tertiary care outpatient setting was low, at 4%. According to the study's comprehensive assessment, severity of COPD was the only factor associated with depression in patients with COPD.
慢性阻塞性气道疾病(COPD)已被发现与抑郁症有关。COPD与抑郁症的重叠可能导致生活质量下降和死亡率增加。一项荟萃分析发现,COPD患者抑郁症的患病率和危险因素具有高度异质性,并且在三级护理医院门诊环境中有限。因此,本研究旨在利用三级护理医院门诊环境中的个人数据评估COPD患者抑郁症的患病率和危险因素。
这项横断面研究纳入了根据GOLD指南被诊断为COPD的成年患者,在过去4周内功能状态稳定且治疗方案相同,并且没有其他严重内科或外科疾病史。根据医院焦虑抑郁量表(HADS)得分11分或更高来诊断抑郁症。然后计算抑郁症的患病率和预测因素。
该研究招募并评估了150例COPD患者,其中6例(4%)患有抑郁症。虽然抑郁症的预测模型包含两个因素,但只有COPD的严重程度与抑郁症独立相关。COPD严重程度的调整后优势比为5.20(95%置信区间为1.75, 15.42;p = 0.003)。
在三级护理门诊环境中,COPD患者抑郁症的患病率较低,为4%。根据该研究的综合评估,COPD的严重程度是COPD患者中与抑郁症相关的唯一因素。