Wexler H, Carter W T, Finegold S M
J Antimicrob Chemother. 1985 Jun;15 Suppl C:173-6. doi: 10.1093/jac/15.suppl_c.173.
The in-vitro activity of Sch 34343, was compared with that of imipenem against 226 strains of anaerobic bacteria. Sch 34343 was identical in activity to imipenem, inhibiting 99.5% of the organisms tested at 16 mg/l (the breakpoint for both drugs). Imipenem was slightly more active than Sch 34343 against Bacteroides, Fusobacterium and Veillonella, although both drugs inhibited all organisms in these groups below breakpoint levels.
将舒巴坦 34343 的体外活性与亚胺培南对 226 株厌氧菌的活性进行了比较。舒巴坦 34343 的活性与亚胺培南相同，在 16mg/l（两种药物的折点）时抑制了 99.5%的受试菌。亚胺培南对拟杆菌属、梭杆菌属和韦荣球菌属的活性略高于舒巴坦 34343，尽管两种药物在折点水平以下均抑制了这些菌群中的所有细菌。
