天然药用植物产品作为免疫增强剂：减轻新冠疫情影响的潜在作用。
Natural medicinal plant products as an immune-boosters: A possible role to lessen the impact of Covid-19.
作者信息
Islam Sk Saruk, Midya Sujoy, Sinha Sanjit, Saadi Sk Md Abu Imam
机构信息
Department of Plant Pathology, Bidhan Chandra Krishi Viswavidyalaya, Mohanpur, 741235, West Bengal, India.
Department of Zoology, Raja N.L. Khan Women's College, Midnapore, West Bengal, 721102, India.
出版信息
Case Stud Chem Environ Eng. 2021 Dec;4:100105. doi: 10.1016/j.cscee.2021.100105. Epub 2021 May 5.
Transmissible Covid-19, caused by novel corona virus since last of 2019 has outspread widely until now. Where, India was the second most affected country and 3rd in mortality rate. In world ancient history, medicinal plants were played a crucial role to cure several diseases. In present study, we show some novel natural medicinal plant metabolites as the potential inhibitors against papain-like protease (PLpro), main protease (Mpro) and RNA-dependent RNA polymerase (RdRp), transmembrane proteinase Serine 2 (TMPRSS2) and angiotensin converting enzyme-2 (ACE-2) of Covid-19. Plant metabolites were having been proven to inhibit SARS-CoVs, which also actively walkable against Covid-19.
自2019年末以来，由新型冠状病毒引起的可传播性新冠病毒至今已广泛传播。其中，印度是受影响第二严重的国家，死亡率位居第三。在世界古代历史中，药用植物在治疗多种疾病方面发挥了关键作用。在本研究中，我们展示了一些新型天然药用植物代谢产物作为针对新冠病毒的木瓜蛋白酶样蛋白酶（PLpro）、主要蛋白酶（Mpro）、RNA依赖性RNA聚合酶（RdRp）、跨膜丝氨酸蛋白酶2（TMPRSS2）和血管紧张素转换酶2（ACE-2）的潜在抑制剂。植物代谢产物已被证明可抑制严重急性呼吸综合征冠状病毒（SARS-CoV），对新冠病毒也有积极作用。
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