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激光在脱发治疗中的应用:已确立疗法的综述及治疗进展。

Lasers in the management of alopecia: a review of established therapies and advances in treatment.

机构信息

Dr. Phillip Frost Department of Dermatology and Cutaneous Surgery, Miller School of Medicine, University of Miami, 1600 NW 10th Ave, 33136, Miami, FL, USA.

University of Missouri-Kansas City School of Medicine, Kansas City, MO, USA.

出版信息

Lasers Med Sci. 2024 Apr 17;39(1):102. doi: 10.1007/s10103-024-04054-7.

DOI:10.1007/s10103-024-04054-7
PMID:38630348
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11023987/
Abstract

Alopecia, also known as hair loss, is a highly prevalent condition affecting millions of men and women in the United States and worldwide, making it one of the most common complaints by patients presenting to a dermatologist. The symptomology on the presentation of alopecia can be highly variable, ranging from diffuse thinning of hair, discrete and localized patches completely absent of hair, or noticing significant shedding when brushing and showering. Although alopecia does not have a direct negative health impact on patients, it is nonetheless a debilitating disease as it can profoundly impact an individual's self-image and psychosocial well-being. There are multiple treatment options available to patients with alopecia, and they are typically tailored to the patient's needs and preferences. The most common of these is the Food and Drug Administration-approved drugs for alopecia, minoxidil, and finasteride. However, both of these are known to be partially efficacious for all patients, so clinicians often use different modalities in conjunction with them, in particular laser-based therapies. This review article will provide a comprehensive assessment of lasers and other light therapies that may be used to manage the two most common types of alopecia: androgenetic alopecia and alopecia areata.

摘要

脱发,也称为头发稀疏,是一种在美国和全球范围内影响数以百万计男性和女性的高度普遍的疾病,是皮肤科医生接诊患者时最常见的症状之一。脱发的症状表现可能高度多样化,包括头发弥漫性变薄、离散且局限的秃斑,或在梳头和洗澡时明显脱发。尽管脱发不会对患者的健康产生直接的负面影响,但它仍然是一种使人虚弱的疾病,因为它会严重影响个人的形象和心理健康。脱发患者有多种治疗选择,这些选择通常根据患者的需求和偏好量身定制。其中最常见的是美国食品和药物管理局批准的脱发药物,米诺地尔和非那雄胺。然而,这两种药物对所有患者的疗效都不尽相同,因此临床医生通常会将其与其他治疗方式联合使用,特别是激光疗法。本文将全面评估激光和其他光疗方法,用于治疗两种最常见的脱发类型:雄激素性脱发和斑秃。

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A prospective randomized half-body study: 308 nm LED light vs. 308 nm excimer laser for localized psoriasis.一项前瞻性随机半身研究:308纳米发光二极管光与308纳米准分子激光治疗局限性银屑病的对比
Front Med (Lausanne). 2023 Nov 6;10:1275912. doi: 10.3389/fmed.2023.1275912. eCollection 2023.
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Alopecia Areata: Current Treatments and New Directions.斑秃:现有治疗方法和新方向。
Am J Clin Dermatol. 2023 Nov;24(6):895-912. doi: 10.1007/s40257-023-00808-1. Epub 2023 Aug 22.
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Arch Dermatol Res. 2023 Apr;315(3):505-511. doi: 10.1007/s00403-022-02393-5. Epub 2022 Sep 17.
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