次氯酸：一种抗原头节的新型制剂。
Hypochlorous Acid: A Novel Agent Against Protoscoleces.
作者信息
Gökçe Oruç Numan, Çetin Kenan, Taş Şükrü, Alkan Sevil, Dinç Uğur
机构信息
Department of General Surgery, Çanakkale Onsekiz Mart University School of Medicine, Çanakkale, Turkey.
Department of Infectious Disease and Clinical Microbiology, Çanakkale Onsekiz Mart University School of Medicine, Çanakkale, Turkey.
出版信息
Infect Dis Clin Microbiol. 2023 Jun 23;5(2):158-164. doi: 10.36519/idcm.2023.238. eCollection 2023 Jun.
OBJECTIVE
We aimed to determine the scolicidal effect of hypochlorous acid and its efficiency at different concentrations.
MATERIALS AND METHODS
We tested the effectiveness of hypochlorous acid in-vitro on sterile gauze at different concentrations in test tubes. In addition, we compared its effectiveness with the scolicidal activity of other agents, povidone-iodine 10% and chlorhexidine-gluconate 0.04%.
RESULTS
Hypochlorous acid was 100% effective in 5 minutes at 1/1 (200 ppm/mL), 1/10 (20 ppm/ml), and 1/100 (2 ppm/mL) concentrations and in 10 minutes at 1/1000 (0.2 ppm/mL) concentration. Povidone-iodine 10%, and chlorhexidine-gluconate 0.04% were studied undiluted and were effective at all study times. Hypochlorous acid maintained the same scolicidal activity on gauze at all study times at the described dilutions.
CONCLUSION
Hypochlorous acid is an effective scolicidal agent in 5 minutes at even 1/100 concentrations. In addition, it maintains the same scolicidal activity on gauze used in surgery to wall the surgical site.
目的
我们旨在确定次氯酸的杀绦虫效果及其在不同浓度下的有效性。
材料与方法
我们在试管中测试了不同浓度的次氯酸在体外对无菌纱布的有效性。此外，我们将其有效性与其他药剂（10%聚维酮碘和0.04%葡萄糖酸氯己定）的杀绦虫活性进行了比较。
结果
次氯酸在1/1（200 ppm/mL）、1/10（20 ppm/mL）和1/100（2 ppm/mL）浓度下5分钟内100%有效，在1/1000（0.2 ppm/mL）浓度下10分钟内100%有效。未稀释研究了10%聚维酮碘和0.04%葡萄糖酸氯己定，且在所有研究时间均有效。在所描述的稀释度下，次氯酸在所有研究时间对纱布均保持相同的杀绦虫活性。
结论
次氯酸即使在1/100浓度下5分钟内也是一种有效的杀绦虫剂。此外，它在用于手术中隔离手术部位的纱布上保持相同的杀绦虫活性。
Zotero 插件