School of Automation, Northwestern Polytechnical University, Xi'an, China.
School of Life Science and Technology, MOE Key Lab for Neuroinformation, University of Electronic Science and Technology of China, Chengdu, China.
Elife. 2024 Apr 18;12:RP90182. doi: 10.7554/eLife.90182.
Cortical folding is an important feature of primate brains that plays a crucial role in various cognitive and behavioral processes. Extensive research has revealed both similarities and differences in folding morphology and brain function among primates including macaque and human. The folding morphology is the basis of brain function, making cross-species studies on folding morphology important for understanding brain function and species evolution. However, prior studies on cross-species folding morphology mainly focused on partial regions of the cortex instead of the entire brain. Previously, our research defined a whole-brain landmark based on folding morphology: the gyral peak. It was found to exist stably across individuals and ages in both human and macaque brains. Shared and unique gyral peaks in human and macaque are identified in this study, and their similarities and differences in spatial distribution, anatomical morphology, and functional connectivity were also dicussed.
脑回是灵长类大脑的一个重要特征，在各种认知和行为过程中起着关键作用。大量研究揭示了猕猴和人类等灵长类动物在脑回形态和脑功能上的相似性和差异性。脑回形态是脑功能的基础，因此对脑回形态的跨物种研究对于理解脑功能和物种进化非常重要。然而，之前关于跨物种脑回形态的研究主要集中在大脑的部分区域，而不是整个大脑。此前，我们的研究基于脑回形态定义了一个全脑标志点：脑回峰。研究发现，在人类和猕猴大脑中，脑回峰在个体和年龄之间都稳定存在。本研究确定了人类和猕猴共享和独特的脑回峰，并讨论了它们在空间分布、解剖形态和功能连接上的相似性和差异性。
