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硫代吡咯宁在酿酒酵母中的光动力作用诱导突变

Induction of mutations by photodynamic action of thiopyronine in Saccharomyces cerevisiae.

作者信息

Kenter D, Laskowski W

出版信息

Radiat Environ Biophys. 1978 Dec 22;15(4):379-85. doi: 10.1007/BF01323462.

DOI:10.1007/BF01323462
PMID:386415
Abstract

The induction of cytoplasmic and nuclear mutations by the photodynamic action of thiopyronine is demonstrated in a haploid strain of Saccharomyces cerevisiae that has been isolated as a photodynamic sensitive mutant. No significant increase in corresponding mutation frequencies could be observed in a strain resistant to photodynamic inactivation by thiopyronine.

摘要

在已分离出的作为光动力敏感突变体的酿酒酵母单倍体菌株中,证实了硫代吡咯宁的光动力作用可诱导细胞质和细胞核突变。在对硫代吡咯宁的光动力失活具有抗性的菌株中,未观察到相应突变频率有显著增加。

相似文献

1
Induction of mutations by photodynamic action of thiopyronine in Saccharomyces cerevisiae.硫代吡咯宁在酿酒酵母中的光动力作用诱导突变
Radiat Environ Biophys. 1978 Dec 22;15(4):379-85. doi: 10.1007/BF01323462.
2
Photosensitivity in thiopyronine-resistant yeast mutants.
J Gen Microbiol. 1983 Jan;129(1):63-73. doi: 10.1099/00221287-129-1-63.
3
[Distribution of [3H] thiopyronine in yeast cells (Saccharomyces cerevisiae)].[3H]硫代吡咯宁在酵母细胞(酿酒酵母)中的分布
Z Naturforsch C Biosci. 1976 Jul-Aug;31(7-8):481-3. doi: 10.1515/znc-1976-7-826.
4
Thiopyronine and 8-methoxypsoralen sensitized photodynamic effect on DNA synthesis in yeast.
Radiat Environ Biophys. 1985;24(2):157-60. doi: 10.1007/BF01229822.
5
Thiopyronine-sensitized photodynamic effect on RNA synthesis in Saccharomyces cells in vivo.硫代吡咯宁致敏光动力作用对体内酿酒酵母细胞RNA合成的影响
Int J Radiat Biol Relat Stud Phys Chem Med. 1981 Jul;40(1):1-9.
6
Thiopyronine- and 8-methoxypsoralen-sensitized photodynamic effect on cell growth, colony forming ability and RNA synthesis in Saccharomyces mutants deficient in DNA repair.硫代吡咯宁和8-甲氧基补骨脂素对DNA修复缺陷的酿酒酵母突变体的细胞生长、集落形成能力及RNA合成的光动力效应。
Photochem Photobiol. 1994 Jun;59(6):627-30. doi: 10.1111/j.1751-1097.1994.tb09667.x.
7
Thiopyronine sensitized photodynamic effect on ribosome synthesis and ribosome content in Saccharomyces cells.
Radiat Environ Biophys. 1981;19(3):181-6. doi: 10.1007/BF01324185.
8
Genotoxicity of bergapten and bergamot oil in Saccharomyces cerevisiae.补骨脂素和佛手柑油对酿酒酵母的遗传毒性。
J Photochem Photobiol B. 1990 Nov;7(2-4):209-29. doi: 10.1016/1011-1344(90)85158-s.
9
Singlet oxygen production and photobiological effects of pinacyanol chloride on yeast Saccharomyces cerevisiae.氯化藻红蛋白对酿酒酵母的单线态氧产生及光生物学效应
J Pharmacobiodyn. 1990 May;13(5):316-20. doi: 10.1248/bpb1978.13.316.
10
UV-induced reactivation and mutagenesis of lambda-phages after treatment with 8-methoxypsoralen or thiopyronine and light.用8-甲氧基补骨脂素或硫代吡咯并光照处理后λ噬菌体的紫外线诱导复活和诱变
Radiat Environ Biophys. 1981;19(4):239-45. doi: 10.1007/BF01324089.

本文引用的文献

1
[THE EFFECT OF THIOPYRONINE ON SACCHAROMYCES STRAINS OF DIFFERENT PLOIDY, ON NUCLEIC ACIDS AND NUCLEIC ACID COMPONENTS IN THE PRESENCE AND ABSENCE OF VISIBLE LIGHT].[硫代吡咯宁在有无可见光情况下对不同倍性酵母菌菌株、核酸及核酸成分的影响]
Z Naturforsch B. 1964 Sep;19:838-44.
2
[Non-mutagenicity of thiopyronin in a forward- and backward mutation system of yeast].
Naturwissenschaften. 1966 Apr;53(7):185. doi: 10.1007/BF00631488.
3
Mode of photosensitizing action of furocoumarins.呋喃香豆素的光敏作用模式。
Photophysiology. 1972(7):115-47.
4
[Synthesis of RNA in Saccharomyces after photodynamic treatment or irradiation with x-rays (author's transl)].
Biophysik. 1973;10(3):249-56. doi: 10.1007/BF01190584.
5
Structural specificity in the lethal and mutagenic activity of furocoumarins in yeast cells.呋喃香豆素在酵母细胞中的致死和诱变活性的结构特异性
Radiat Environ Biophys. 1975 Oct 2;12(3):241-52. doi: 10.1007/BF01327351.