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鱼类健康的免疫和分子诊断技术:现状和未来展望。

Immunological and molecular diagnostic techniques in fish health: present and future prospectus.

机构信息

Division of Aquatic Animal Health Management, Faculty of Fisheries, SKUAST-K, Rangil, Ganderbal, Jammu and Kashmir, 190006, India.

Division of Aquatic Environmental Management, Faculty of Fisheries, SKUAST-K, Rangil, Ganderbal, Jammu and Kashmir, 190006, India.

出版信息

Mol Biol Rep. 2024 Apr 20;51(1):551. doi: 10.1007/s11033-024-09344-5.

Abstract

Fish health management is critical to aquaculture and fisheries as it directly affects sustainability and productivity. Fish disease diagnosis has taken a massive stride because of advances in immunological and molecular diagnostic tools which provide a sensitive, quick, and accurate means of identifying diseases. This review presents an overview of the main molecular and immunological diagnostic methods for determining the health of fish. The immunological techniques help to diagnose different fish diseases by detecting specific antigens and antibodies. The application of immunological techniques to vaccine development is also examined in this review. The genetic identification of pathogens is made possible by molecular diagnostic techniques that enable the precise identification of bacterial, viral, and parasitic organisms in addition to evaluating host reactions and genetic variation associated with resistance to disease. The combination of molecular and immunological methods has resulted in the creation of novel techniques for thorough evaluation of fish health. These developments improve treatment measures, pathogen identification and provide new information about the variables affecting fish health, such as genetic predispositions and environmental stresses. In the framework of sustainable fish farming and fisheries management, this paper focuses on the importance of these diagnostic techniques that play a crucial role in protecting fish populations and the aquatic habitats. This review also examines the present and potential future directions in immunological and molecular diagnostic techniques in fish health.

摘要

鱼类健康管理对水产养殖和渔业至关重要,因为它直接影响可持续性和生产力。由于免疫学和分子诊断工具的进步,鱼类疾病诊断取得了巨大进展,这些工具提供了一种敏感、快速和准确的疾病识别方法。 本综述介绍了用于确定鱼类健康的主要分子和免疫学诊断方法的概述。免疫学技术通过检测特定的抗原和抗体来帮助诊断不同的鱼类疾病。本综述还检查了免疫学技术在疫苗开发中的应用。分子诊断技术可实现病原体的遗传鉴定,除了评估与疾病抗性相关的宿主反应和遗传变异外,还能够精确识别细菌、病毒和寄生虫。 分子和免疫学方法的结合已经产生了用于全面评估鱼类健康的新技术。这些发展改进了治疗措施、病原体鉴定,并提供了有关影响鱼类健康的变量的新信息,例如遗传倾向和环境压力。 在可持续水产养殖和渔业管理的框架内,本文重点介绍了这些诊断技术的重要性,这些技术在保护鱼类种群和水生栖息地方面发挥着关键作用。本综述还研究了鱼类健康中免疫学和分子诊断技术的现状和潜在未来方向。

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