血红蛋白与红细胞分布宽度比值（HRR）和红细胞分布宽度与白蛋白比值（RAR）在心包炎中的临床相关性。
Clinical relevance of HRR (hemoglobin to RDW) and RAR (RDW to albumin) in pericarditis.
作者信息
Eyiol Hatice, Eyiol Azmi, Sahin Ahmet Taha
机构信息
Department of Anesthesiology, Beyhekim Training and Research Hospital, Konya, Turkey.
Department of Cardiology, Beyhekim Training and Research Hospital, Konya, Turkey.
出版信息
Biomark Med. 2025 Mar;19(6):197-204. doi: 10.1080/17520363.2025.2471743. Epub 2025 Feb 27.
AIM
This study evaluated the Hemoglobin to Red Cell Distribution Width Ratio (HRR) and Red Cell Distribution Width to Albumin Ratio (RAR) in acute pericarditis patients, exploring associations with clinical parameters.
METHODS
A retrospective cohort study included 257 patients diagnosed with acute pericarditis (2015-2023). Data on hemoglobin, RDW, albumin, treatments, hospital stay, and recurrence were analyzed using SPSS 27.0.
RESULTS
The mean age was 41 years. HRR averaged 1.067 ± 0.142, and RAR was 0.311. Men had higher hemoglobin and albumin levels, while women had higher platelet and HDL levels. Lower HRR correlated with severe conditions and recurrence, while higher RAR was linked to disease severity and recurrence. Both markers were strongly associated with pericardial effusion and IV steroid need.
CONCLUSION
HRR and RAR are valuable biomarkers in acute pericarditis, aiding in assessing disease severity and guiding treatment.
目的
本研究评估了急性心包炎患者的血红蛋白与红细胞分布宽度比值（HRR）和红细胞分布宽度与白蛋白比值（RAR），探讨其与临床参数的相关性。
方法
一项回顾性队列研究纳入了257例诊断为急性心包炎的患者（2015年至2023年）。使用SPSS 27.0分析血红蛋白、红细胞分布宽度、白蛋白、治疗、住院时间和复发的数据。
结果
平均年龄为41岁。HRR平均为1.067±0.142，RAR为0.311。男性的血红蛋白和白蛋白水平较高，而女性的血小板和高密度脂蛋白水平较高。较低的HRR与病情严重程度和复发相关，而较高的RAR与疾病严重程度和复发有关。这两个标志物均与心包积液和静脉使用类固醇密切相关。
结论
HRR和RAR是急性心包炎中有价值的生物标志物，有助于评估疾病严重程度并指导治疗。
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