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血红蛋白与红细胞分布宽度比值(HRR)和红细胞分布宽度与白蛋白比值(RAR)在心包炎中的临床相关性。

Clinical relevance of HRR (hemoglobin to RDW) and RAR (RDW to albumin) in pericarditis.

作者信息

Eyiol Hatice, Eyiol Azmi, Sahin Ahmet Taha

机构信息

Department of Anesthesiology, Beyhekim Training and Research Hospital, Konya, Turkey.

Department of Cardiology, Beyhekim Training and Research Hospital, Konya, Turkey.

出版信息

Biomark Med. 2025 Mar;19(6):197-204. doi: 10.1080/17520363.2025.2471743. Epub 2025 Feb 27.

DOI:10.1080/17520363.2025.2471743
PMID:40013601
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11916353/
Abstract

AIM

This study evaluated the Hemoglobin to Red Cell Distribution Width Ratio (HRR) and Red Cell Distribution Width to Albumin Ratio (RAR) in acute pericarditis patients, exploring associations with clinical parameters.

METHODS

A retrospective cohort study included 257 patients diagnosed with acute pericarditis (2015-2023). Data on hemoglobin, RDW, albumin, treatments, hospital stay, and recurrence were analyzed using SPSS 27.0.

RESULTS

The mean age was 41 years. HRR averaged 1.067 ± 0.142, and RAR was 0.311. Men had higher hemoglobin and albumin levels, while women had higher platelet and HDL levels. Lower HRR correlated with severe conditions and recurrence, while higher RAR was linked to disease severity and recurrence. Both markers were strongly associated with pericardial effusion and IV steroid need.

CONCLUSION

HRR and RAR are valuable biomarkers in acute pericarditis, aiding in assessing disease severity and guiding treatment.

摘要

目的

本研究评估了急性心包炎患者的血红蛋白与红细胞分布宽度比值(HRR)和红细胞分布宽度与白蛋白比值(RAR),探讨其与临床参数的相关性。

方法

一项回顾性队列研究纳入了257例诊断为急性心包炎的患者(2015年至2023年)。使用SPSS 27.0分析血红蛋白、红细胞分布宽度、白蛋白、治疗、住院时间和复发的数据。

结果

平均年龄为41岁。HRR平均为1.067±0.142,RAR为0.311。男性的血红蛋白和白蛋白水平较高,而女性的血小板和高密度脂蛋白水平较高。较低的HRR与病情严重程度和复发相关,而较高的RAR与疾病严重程度和复发有关。这两个标志物均与心包积液和静脉使用类固醇密切相关。

结论

HRR和RAR是急性心包炎中有价值的生物标志物,有助于评估疾病严重程度并指导治疗。

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引用本文的文献

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Letter to the editor on the article "Clinical relevance of HRR and RAR in pericarditis" by Hatice Eyiol et al.致编辑的信:关于哈提斯·埃约尔等人所著文章《心包炎中HRR和RAR的临床相关性》
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Pericarditis and inflammatory biomarkers.心包炎与炎症生物标志物
Biomark Med. 2025 May;19(10):357-358. doi: 10.1080/17520363.2025.2494498. Epub 2025 Apr 17.

本文引用的文献

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J Clin Med. 2024 Oct 6;13(19):5944. doi: 10.3390/jcm13195944.
2
Diagnosis, Risk Stratification, and Treatment of Pericarditis: A Review.心包炎的诊断、风险分层与治疗:综述
JAMA. 2024 Oct 1;332(13):1090-1100. doi: 10.1001/jama.2024.12935.
3
Association of red blood cell distribution width to albumin ratio with prognosis in stroke patients.红细胞分布宽度与白蛋白比值与卒中患者预后的关系
Biomark Med. 2024;18(7):311-320. doi: 10.2217/bmm-2023-0460. Epub 2024 Apr 22.
4
The relationship between hemoglobin-to-red cell distribution width (RDW) ratio (HRR) and mortality in stroke patients.血红蛋白与红细胞分布宽度比值(HRR)与脑卒中患者死亡率的关系。
Eur Rev Med Pharmacol Sci. 2024 Feb;28(4):1504-1512. doi: 10.26355/eurrev_202402_35480.
5
Red blood cell distribution width (RDW) - A new nutritional biomarker to assess nutritional risk and response to nutritional therapy?红细胞分布宽度(RDW)- 评估营养风险和营养治疗反应的新营养生物标志物?
Clin Nutr. 2024 Feb;43(2):575-585. doi: 10.1016/j.clnu.2024.01.001. Epub 2024 Jan 5.
6
Association between red blood cell distribution width to albumin ratio and prognosis of patients with sepsis: A retrospective cohort study.红细胞分布宽度与白蛋白比值和脓毒症患者预后的相关性:一项回顾性队列研究。
Front Nutr. 2022 Sep 23;9:1019502. doi: 10.3389/fnut.2022.1019502. eCollection 2022.
7
Low Hemoglobin-to-Red Cell Distribution Width Ratio Is Associated with Mortality in Patients with HBV-Related Decompensated Cirrhosis.低血红蛋白与红细胞分布宽度比值与 HBV 相关失代偿性肝硬化患者的死亡率相关。
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The red blood cell distribution width-albumin ratio: A promising predictor of mortality in heart failure patients - A cohort study.红细胞分布宽度-白蛋白比值:心力衰竭患者死亡率的有前途的预测指标-一项队列研究。
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Association Between Red Blood Cell Distribution Width-to-Albumin Ratio and Prognosis of Patients with Aortic Aneurysms.红细胞分布宽度与白蛋白比值和主动脉瘤患者预后的关系
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The Red Blood Cell Distribution Width-Albumin Ratio: A Promising Predictor of Mortality in Stroke Patients.红细胞分布宽度-白蛋白比值:中风患者死亡率的一个有前景的预测指标。
Int J Gen Med. 2021 Jul 22;14:3737-3747. doi: 10.2147/IJGM.S322441. eCollection 2021.