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Patient vulnerability in stereotactic arrhythmia radioablation (STAR): a preliminary ethical appraisal from the STOPSTORM.eu consortium.立体定向心律失常放射消融术（STAR）中的患者脆弱性：来自 STOPSTORM.eu 联盟的初步伦理评估。

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Refining critical structure contouring in STereotactic Arrhythmia Radioablation (STAR): Benchmark results and consensus guidelines from the STOPSTORM.eu consortium.优化立体定向心律失常放射消融（STAR）中的关键结构勾画：来自 STOPSTORM.eu 联盟的基准结果和共识指南。

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Refining Treatment Planning in STereotactic Arrhythmia Radioablation: Benchmark Results and Consensus Statement From the STOPSTORM.eu Consortium.优化立体定向心律失常射频消融治疗计划：STOPSTORM.eu联盟的基准结果与共识声明

Int J Radiat Oncol Biol Phys. 2025 Jan 1;121(1):218-229. doi: 10.1016/j.ijrobp.2024.07.2331. Epub 2024 Aug 8.

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Institutional experience report on the target contouring workflow in the radiotherapy department for stereotactic arrhythmia radioablation delivered on conventional linear accelerators.常规线性加速器立体定向心律失常放射消融治疗中的靶区勾画工作流程的机构经验报告。

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Implementing stereotactic arrhythmia radioablation with STOPSTORM.eu consortium support: intermediate results of a prospective Israeli single-institutional trial.在STOPSTORM.eu联盟的支持下实施立体定向心律失常射频消融术：一项以色列单中心前瞻性试验的中期结果

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Electroanatomical mapping after cardiac radioablation for treatment of incessant electrical storm: a case report from the RAVENTA trial.心脏射频消融治疗持续性电风暴后的电解剖标测：来自 RAVENTA 试验的一例报告。

Strahlenther Onkol. 2023 Nov;199(11):1018-1024. doi: 10.1007/s00066-023-02136-z. Epub 2023 Sep 12.

2

Radiosurgery for ventricular tachycardia (RAVENTA): interim analysis of a multicenter multiplatform feasibility trial.放射外科治疗室性心动过速（RAVENTA）：多中心多平台可行性试验的中期分析。

Strahlenther Onkol. 2023 Jul;199(7):621-630. doi: 10.1007/s00066-023-02091-9. Epub 2023 Jun 7.

3

STereotactic Arrhythmia Radioablation (STAR): the Standardized Treatment and Outcome Platform for Stereotactic Therapy Of Re-entrant tachycardia by a Multidisciplinary consortium (STOPSTORM.eu) and review of current patterns of STAR practice in Europe.立体定向心律失常消融（STAR）：多学科联盟立体定向治疗折返性心动过速的标准化治疗和结果平台（STOPSTORM.eu），以及对欧洲当前 STAR 实践模式的回顾。

Europace. 2023 Apr 15;25(4):1284-1295. doi: 10.1093/europace/euac238.

4

Recommendations regarding cardiac stereotactic body radiotherapy for treatment refractory ventricular tachycardia.针对治疗抵抗性室性心动过速的心脏立体定向体部放疗推荐建议。

Heart Rhythm. 2021 Dec;18(12):2137-2145. doi: 10.1016/j.hrthm.2021.08.004. Epub 2021 Aug 8.

5

Stereotactic radioablation of ventricular arrhythmias in patients with structural heart disease - A systematic review.立体定向放射消融治疗结构性心脏病患者室性心律失常的系统评价。

Radiother Oncol. 2021 Sep;162:132-139. doi: 10.1016/j.radonc.2021.06.036. Epub 2021 Jul 4.

6

Non-invasive ablation of arrhythmias with stereotactic ablative radiotherapy.立体定向消融放疗用于心律失常的非侵入性消融

Trends Cardiovasc Med. 2022 Jul;32(5):287-296. doi: 10.1016/j.tcm.2021.04.008. Epub 2021 May 2.

7

Clinical Evidence behind Stereotactic Radiotherapy for the Treatment of Ventricular Tachycardia (STAR)-A Comprehensive Review.立体定向放射治疗心室性心动过速（STAR）的临床证据——全面综述

J Clin Med. 2021 Mar 17;10(6):1238. doi: 10.3390/jcm10061238.

8

Safety and Outcomes of Ventricular Tachycardia Substrate Ablation During Sinus Rhythm: A Prospective Multicenter Registry.窦性心律时室性心动过速基质消融的安全性和结果：一项前瞻性多中心登记研究。

JACC Clin Electrophysiol. 2020 Oct 26;6(11):1435-1448. doi: 10.1016/j.jacep.2020.07.028.

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Stereotactic Radiotherapy for the Management of Refractory Ventricular Tachycardia: Promise and Future Directions.立体定向放射疗法用于难治性室性心动过速的治疗：前景与未来方向

Front Cardiovasc Med. 2020 Jun 25;7:108. doi: 10.3389/fcvm.2020.00108. eCollection 2020.

10

Relational ethics in palliative care research: including a person-centred approach.姑息治疗研究中的关系伦理：纳入以患者为中心的方法。

Palliat Care Soc Pract. 2019 Dec 19;13:2632352419885384. doi: 10.1177/2632352419885384. eCollection 2019.

立体定向心律失常放射消融术（STAR）中的患者脆弱性：来自 STOPSTORM.eu 联盟的初步伦理评估。

Patient vulnerability in stereotactic arrhythmia radioablation (STAR): a preliminary ethical appraisal from the STOPSTORM.eu consortium.

机构信息

Research Unit on Everyday Bioethics and Ethics of Science, Department of Legal Sciences, University of Florence, Florence, Italy.

Legal Medicine and Bioethics, Azienda USL-IRCCS di Reggio Emilia, Reggio Emilia, Italy.

出版信息

Strahlenther Onkol. 2024 Oct;200(10):903-907. doi: 10.1007/s00066-024-02230-w. Epub 2024 Apr 23.

DOI:10.1007/s00066-024-02230-w

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11442478/

Abstract

This preliminary ethical appraisal from the STOPSTORM.eu consortium is meant to raise critical points that clinicians administering stereotactic arrhythmia radioablation should consider to meet the highest standards in medical ethics and thus promote quality of life of patients recruited for radiotherapy treatments at a stage in which they experience a significant degree of vulnerability.

摘要

这是 STOPSTORM.eu 联盟的初步伦理评估，旨在提出一些关键问题，以便对接受立体定向心律失常放射消融治疗的临床医生进行提醒，使其在符合最高医学伦理标准的前提下，提升招募到的处于高度脆弱阶段的放射治疗患者的生活质量。