人血小板3H-丙咪嗪结合的变异
Variation in human platelet 3H-imipramine binding.
作者信息
Tang S W, Morris J M
出版信息
Psychiatry Res. 1985 Oct;16(2):141-6. doi: 10.1016/0165-1781(85)90007-1.
PMID:3865254
Abstract
Platelet 3H-imipramine binding values from 45 normal controls and 20 depressed subjects were collected over a 2-year period. During this time, wide inter-individual variations in the affinity constant (Kd) and maximal number of binding sites (Bmax) were observed in the control population; however, we failed to observe a seasonal change in platelet 3H-imipramine binding. The Kd and Bmax values of depressed subjects were not significantly different from those of controls.
摘要
在两年时间里收集了45名正常对照者和20名抑郁症患者的血小板3H-丙咪嗪结合值。在此期间，在对照人群中观察到亲和常数（Kd）和最大结合位点数（Bmax）存在广泛的个体间差异；然而，我们未观察到血小板3H-丙咪嗪结合的季节性变化。抑郁症患者的Kd和Bmax值与对照组无显著差异。
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