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一种用于检测梅毒螺旋体抗体的固相放射免疫测定法。

A solid-phase radioimmunoassay for the detection of antibodies to Treponema pallidum.

作者信息

Miller J M, Donowho E M, Trent D W, Moody E E

出版信息

Sex Transm Dis. 1979 Apr-Jun;6(2):43-9. doi: 10.1097/00007435-197904000-00001.

DOI:10.1097/00007435-197904000-00001
PMID:386532
Abstract

A solid-phase radioimmunoassay (RIA) procedure was developed for the detection of antibodies to Treponema pallidum. The source of antigen used was T. pallidum (Nichols strain), which was specifically bound to the solid phase by use of rabbit antibody to T. pallidum (Nichols strain). The solid-phase system for this RIA test is the well of a microtiter plate. Preliminary data suggest that the RIA procedure is sensitive and specific and might be a useful addition to the research tools and serologic tests used in the study and diagnosis of syphilis.

摘要

已开发出一种固相放射免疫测定（RIA）程序用于检测梅毒螺旋体抗体。所用抗原来源为梅毒螺旋体（Nichols株），通过使用兔抗梅毒螺旋体（Nichols株）抗体将其特异性结合到固相上。该RIA检测的固相系统是微量滴定板的孔。初步数据表明，该RIA程序灵敏且特异，可能会成为梅毒研究和诊断中所使用的研究工具和血清学检测的有益补充。

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