Kato Renata Tiemi, Rolim-de-Moura Christiane, Allemann Norma
Department of Ophthalmology and Visual Sciences, Federal University of São Paulo, Escola Paulista de Medicina, Rua Botucatu, 806 - Secretaria Administrativa, São Paulo, SP, CEP 04023-062, Brazil.
Sci Rep. 2024 Apr 25;14(1):9551. doi: 10.1038/s41598-024-60320-2.
Primary congenital glaucoma is a rare disease that occurs in early birth and can lead to low vision. Evaluating affected children is challenging and there is a lack of studies regarding color vision in pediatric glaucoma patients. This cross-sectional study included 21 eyes of 13 children with primary congenital glaucoma who were assessed using the Farnsworth D-15 test to evaluate color vision discrimination and by spectral domain optical coherence tomography to measure retinal fiber layer thickness. Age, visual acuity, cup-to-disc ratio and spherical equivalent data were also collected. Global and sectional circumpapillary and macular retinal fiber layer thicknesses were measured and compared based on color vision test performance. Four eyes (19%) failed the color vision test with diffuse dyschromatopsia patterns. Only age showed statistical significance in color vision test performance. Global and sectional circumpapillary and macular retinal fiber layer thicknesses were similar between the color test outcomes dyschromatopsia and normal. While the color vision test could play a role in assessing children with primary congenital glaucoma, further studies are needed to correlate it with damage to retinal fiber layer thickness.
原发性先天性青光眼是一种罕见疾病,发生于婴儿早期,可导致视力低下。评估患病儿童具有挑战性,且缺乏关于小儿青光眼患者色觉的研究。这项横断面研究纳入了13名患有原发性先天性青光眼儿童的21只眼睛,使用 Farnsworth D - 15测试评估色觉辨别能力,并通过光谱域光学相干断层扫描测量视网膜纤维层厚度。同时收集了年龄、视力、杯盘比和等效球镜数据。根据色觉测试表现,测量并比较了视盘周围和黄斑区视网膜纤维层的整体和局部厚度。4只眼睛(19%)色觉测试未通过,呈现弥漫性色觉障碍模式。仅年龄在色觉测试表现方面具有统计学意义。色觉测试结果为色觉障碍和正常的患者,其视盘周围和黄斑区视网膜纤维层的整体和局部厚度相似。虽然色觉测试可能在评估原发性先天性青光眼患儿中发挥作用,但需要进一步研究将其与视网膜纤维层厚度损伤相关联。