Department of Public Health, University of North Florida, Jacksonville, FL, United States.
Department of Public Health, University of North Florida, Jacksonville, FL, United States.
Vaccine. 2024 Jun 11;42(16):3529-3535. doi: 10.1016/j.vaccine.2024.04.070. Epub 2024 Apr 26.
Long-COVID (having symptoms lasting 3 months or longer post-infection) is an emerging public health concern, yet research on whether COVID-19 booster vaccines can mitigate this condition is limited. This study examined associations between booster uptake and long-COVID prevalence among U.S. adults. Data were analyzed from 8757 adults aged 18 years or older with a history of COVID-19 infection from the 2022 National Health Interview Survey. Weighted prevalence and logistic regression models examined relationships between self-reported COVID-19 booster vaccination status and long-COVID, adjusting for sociodemographics and health factors. 19.5 % reported experiencing long-COVID. Individuals receiving the COVID-19 booster vaccine had significantly lower adjusted odds of long-COVID (OR 0.75, 95 % CI 0.61-0.93) compared to unvaccinated individuals. Overall, these findings suggest that COVID-19 booster vaccination is associated with a reduced prevalence of long-COVID among the U.S. adult population, underscoring the importance of optimizing booster uptake to mitigate the long-term impacts of COVID-19.
长新冠（感染后持续 3 个月或更长时间出现症状）是一个新出现的公共卫生关注点，但关于 COVID-19 加强疫苗是否能减轻这种情况的研究有限。本研究调查了美国成年人中加强针接种率与长新冠患病率之间的关联。这项研究的数据来自于 2022 年全国健康访谈调查中 8757 名年龄在 18 岁及以上、有 COVID-19 感染史的成年人。加权患病率和逻辑回归模型检验了自我报告的 COVID-19 加强针接种状况与长新冠之间的关系，调整了社会人口统计学和健康因素。19.5%的人报告经历过长新冠。与未接种疫苗的个体相比，接种 COVID-19 加强针的个体长新冠的调整后比值比显著降低（OR 0.75，95%CI 0.61-0.93）。总的来说，这些发现表明 COVID-19 加强针接种与美国成年人群体中长新冠的患病率降低有关，这突显了优化加强针接种以减轻 COVID-19 的长期影响的重要性。
