基于石墨烯的新型光热水凝胶在生物医学中的应用

Novel Photothermal Graphene-Based Hydrogels in Biomedical Applications.

作者信息

Croitoru Alexa-Maria, Ficai Denisa, Ficai Anton

机构信息

Research Institute of the University of Bucharest (ICUB), University of Bucharest, Spl. Independentei 91-95, 0500957 Bucharest, Romania.

Department of Science and Engineering of Oxide Materials and Nanomaterials, Faculty of Chemical Engineering and Biotechnologies, National University for Science and Technology Politehnica Bucharest, Gh. Polizu St. 1-7, 011061 Bucharest, Romania.

出版信息

Polymers (Basel). 2024 Apr 15;16(8):1098. doi: 10.3390/polym16081098.

DOI:10.3390/polym16081098

PMID:38675017

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11053615/

Abstract

In the last decade, photothermal therapy (PTT) has attracted tremendous attention because it is non-invasive, shows high efficiency and antibacterial activity, and minimizes drug side effects. Previous studies demonstrated that PTT can effectively inhibit the growth of bacteria and promotes cell proliferation, accelerating wound healing and tissue regeneration. Among different NIR-responsive biomaterials, graphene-based hydrogels with photothermal properties are considered as the best candidates for biomedical applications, due to their excellent properties. This review summarizes the current advances in the development of innovative graphene-based hydrogels for PTT-based biomedical applications. Also, the information about photothermal properties and the potential applications of graphene-based hydrogels in biomedical therapies are provided. These findings provide a great potential for supporting their applications in photothermal biomedicine.

摘要

在过去十年中，光热疗法（PTT）因其无创、高效、具有抗菌活性且能将药物副作用降至最低而备受关注。先前的研究表明，PTT可有效抑制细菌生长并促进细胞增殖，加速伤口愈合和组织再生。在不同的近红外响应生物材料中，具有光热特性的石墨烯基水凝胶因其优异的性能被认为是生物医学应用的最佳候选材料。本综述总结了用于基于PTT的生物医学应用的创新型石墨烯基水凝胶开发的当前进展。此外，还提供了有关石墨烯基水凝胶的光热特性及其在生物医学治疗中的潜在应用的信息。这些发现为支持它们在光热生物医学中的应用提供了巨大潜力。