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一种用于检测人体生物磁性的光泵磁梯度计。

An optically pumped magnetic gradiometer for the detection of human biomagnetism.

作者信息

Cook Harry, Bezsudnova Yulia, Koponen Lari M, Jensen Ole, Barontini Giovanni, Kowalczyk Anna U

机构信息

School of Physics and Astronomy, University of Birmingham, Edgbaston, Birmingham B15 2TT, United Kingdom.

Centre for Human Brain Health, School of Psychology, University of Birmingham, Edgbaston, Birmingham B15 2SA, United Kingdom.

出版信息

Quantum Sci Technol. 2024 Jul 1;9(3):035016. doi: 10.1088/2058-9565/ad3d81. Epub 2024 Apr 26.

DOI:10.1088/2058-9565/ad3d81
PMID:38680502
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11047143/
Abstract

We realise an intrinsic optically pumped magnetic gradiometer based on non-linear magneto-optical rotation. We show that our sensor can reach a gradiometric sensitivity of 18 fT and can reject common mode homogeneous magnetic field noise with up to 30 dB attenuation. We demonstrate that our magnetic field gradiometer is sufficiently sensitive and resilient to be employed in biomagnetic applications. In particular, we are able to record the auditory evoked response of the human brain, and to perform real-time magnetocardiography in the presence of external magnetic field disturbances. Our gradiometer provides complementary capabilities in human biomagnetic sensing to optically pumped magnetometers, and opens new avenues in the detection of human biomagnetism.

摘要

我们实现了一种基于非线性磁光旋转的本征光泵磁梯度计。我们表明，我们的传感器可以达到18 fT的梯度灵敏度，并且可以抑制高达30 dB衰减的共模均匀磁场噪声。我们证明，我们的磁场梯度计足够灵敏且具有弹性，可用于生物磁应用。特别是，我们能够记录人类大脑的听觉诱发反应，并在存在外部磁场干扰的情况下进行实时磁心动图。我们的梯度计在人类生物磁传感方面为光泵磁力计提供了互补能力，并为人类生物磁性的检测开辟了新途径。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f974/11047143/11e762bd8ed9/qstad3d81f6_lr.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f974/11047143/7b415828a743/qstad3d81f1_lr.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f974/11047143/85073f961948/qstad3d81f2_lr.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f974/11047143/7991e04d9210/qstad3d81f3_lr.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f974/11047143/c44f21846a76/qstad3d81f4_lr.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f974/11047143/6b09daf2ca1a/qstad3d81f5_lr.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f974/11047143/11e762bd8ed9/qstad3d81f6_lr.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f974/11047143/7b415828a743/qstad3d81f1_lr.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f974/11047143/85073f961948/qstad3d81f2_lr.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f974/11047143/7991e04d9210/qstad3d81f3_lr.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f974/11047143/c44f21846a76/qstad3d81f4_lr.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f974/11047143/6b09daf2ca1a/qstad3d81f5_lr.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f974/11047143/11e762bd8ed9/qstad3d81f6_lr.jpg

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4
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7
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8
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Neuroimage. 2022 Dec 1;264:119747. doi: 10.1016/j.neuroimage.2022.119747. Epub 2022 Nov 18.
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