Costescu Strachinaru Diana Isabela, Henckaerts Liesbet, Depypere Melissa, Vanbrabant Peter
Center for Infectious Diseases, Queen Astrid Military Hospital, Rue Bruyn 1, 1120, Brussels, Belgium.
Department of General Internal Medicine, KU Leuven, University Hospitals Leuven, Herestraat 49, Leuven, Belgium.
Oxf Med Case Reports. 2024 Apr 25;2024(4):omae032. doi: 10.1093/omcr/omae032. eCollection 2024 Apr.
Tularemia is a zoonotic infection caused by , an aerobic, facultative intracellular coccobacillus, encountered especially in the Northern hemisphere. is a pathogen of humans and hundreds of animal species.
A Belgian traveler returning from an adventurous vacation in Central Europe presents fever, flu-like symptoms, a skin ulcer with a necrotic center resembling an eschar on the left thigh and painful left inguinal lymphadenopathy. An enzyme linked immunosorbent assay developed by the National Reference Laboratory for Tularemia, Sciensano, Belgium, detected elevated Ig G antibodies against , while the rest of the serologies were negative.
A highly likely case of ulceroglandular tularemia is described and the differential diagnosis is discussed.
The incidence of tularemia has been increasing throughout Europe in recent years. Physicians should be aware of this disease, its diversity of reservoirs, transmission routes and clinical presentations.
兔热病是由一种需氧的兼性细胞内球杆菌引起的人畜共患感染，在北半球尤为常见。它是人类和数百种动物的病原体。
一名从欧洲中部冒险度假归来的比利时旅行者出现发热、流感样症状、左大腿有一个坏死中心类似焦痂的皮肤溃疡以及左侧腹股沟淋巴结疼痛。比利时Sciensano国家兔热病参考实验室开发的酶联免疫吸附试验检测到针对该菌的IgG抗体升高，而其他血清学检测均为阴性。
描述了一例高度疑似的溃疡腺型兔热病病例并讨论了鉴别诊断。
近年来兔热病在欧洲的发病率一直在上升。医生应了解这种疾病、其多样的宿主、传播途径和临床表现。
