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一种新型含吡咯官能团的丁香酚衍生物在盐酸溶液中对低碳钢腐蚀的合成、表征及抑制作用

Synthesis, characterization, and inhibition effects of a novel eugenol derivative bearing pyrrole functionalities on the corrosion of mild steel in a HCl acid solution.

作者信息

Rebbah Bahija, El Haib Abderrahim, Lahmady Sara, Forsal Issam, Gouygou Maryse, Mallet-Ladeira Sonia, Medaghri-Alaoui Abdelouahid, Rakib El Mostapha, Hannioui Abdellah

机构信息

Molecular Chemistry, Materials and Catalysis Laboratory, Faculty of Science and Technology, Sultan Moulay Slimane University B.P. 523 Beni Mellal Morocco

Chemical Processes and Applied Materials Laboratory, Polydisciplinary Faculty, Sultan Moulay Slimane University PB: 592 Beni Mellal Morocco.

出版信息

RSC Adv. 2024 Apr 29;14(20):14152-14160. doi: 10.1039/d4ra01337a. eCollection 2024 Apr 25.

DOI:10.1039/d4ra01337a
PMID:38686294
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11057412/
Abstract

Semi-synthetic modifications of natural products have yielded numerous anti-cancer drugs, antimicrobials, and corrosion inhibitors. In this study, eugenol, a natural product, was synthetically modified to generate a novel heterocyclic compound: pyrrole, which forms crystals. The latter is the outcome of the condensation reaction between eugenol hydrazide and 2,5-hexanedione, conducted under reflux ethanol conditions, without a catalyst, achieving a 96% yield. This compound structure was characterized through spectroscopic methods, such as NMR and FTIR, and validated par the crystal's X-ray diffraction analysis. According to the findings of the electrochemical study, pyrrole demonstrated effective inhibition against the carbon steel's corrosion in a 1 M HCl acid solution.

摘要

天然产物的半合成修饰已产生了众多抗癌药物、抗菌剂和腐蚀抑制剂。在本研究中，对天然产物丁香酚进行了合成修饰，以生成一种新型杂环化合物：吡咯，它能形成晶体。后者是丁香酚酰肼与2,5 -己二酮在无催化剂的回流乙醇条件下进行缩合反应的产物，产率达到96%。该化合物结构通过NMR和FTIR等光谱方法进行了表征，并通过晶体的X射线衍射分析进行了验证。根据电化学研究结果，吡咯在1 M HCl酸溶液中对碳钢的腐蚀表现出有效的抑制作用。

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