Tirupathi Sunny Priyatham, Malothu Sardhar, Allaparthi Udaikiran, Velvaluri Swathi, Afnan Lamea, Budia Shraddha, Sachdev Muskaan
Department of Pediatric and Preventive Dentistry, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences (SIMATS), Saveetha University, Chennai, India.
Department of Periodontics, Mamatha Dental College & Hospital, Khammam, India.
J Korean Assoc Oral Maxillofac Surg. 2024 Apr 30;50(2):63-69. doi: 10.5125/jkaoms.2024.50.2.63.
This current systematic review aimed to evaluate the current evidence on the effect of topical capsaicin application to alleviate symptoms related to burning mouth syndrome (BMS). PubMed, Ovid SP, and Cochrane were searched from 1980 to 2022 to identify relevant literature. A total of 942 titles (PubMed, 84; Ovid SP, 839; Cochrane, 19) was retrieved, of which 936 were excluded based on the title and abstract. A total of 11 studies were further evaluated for full text analysis, of which 7 were excluded. As a result, 4 articles were included for qualitative synthesis of data. Capsaicin as a mouthwash can have potential application in the treatment of symptoms related to burning mouth. The quality of available studies is moderate to low, and a well-designed randomized multicentric study comparing capsaicin with other active agents is planned to obtain more definitive conclusions.
本系统评价旨在评估局部应用辣椒素缓解灼口综合征（BMS）相关症状的现有证据。检索了1980年至2022年期间的PubMed、Ovid SP和Cochrane数据库，以识别相关文献。共检索到942篇文献（PubMed 84篇、Ovid SP 839篇、Cochrane 19篇），其中936篇基于标题和摘要被排除。共对11项研究进行全文分析，其中7项被排除。结果，纳入4篇文章进行数据定性综合分析。辣椒素作为漱口水在治疗灼口相关症状方面具有潜在应用价值。现有研究质量为中等至低等，计划开展一项设计良好的将辣椒素与其他活性剂进行比较的随机多中心研究，以得出更明确的结论。
