Department of Cardiology, University Hospital Basel, University of Basel, Petersgraben 4, 4031 Basel, Switzerland.
Cardiovascular Research Institute Basel, University Hospital Basel, University of Basel, Spitalstrasse 2, 4056 Basel, Switzerland.
Europace. 2024 May 2;26(5). doi: 10.1093/europace/euae112.
Arrhythmia-induced cardiomyopathy (AiCM) represents a subtype of acute heart failure (HF) in the context of sustained arrhythmia. Clear definitions and management recommendations for AiCM are lacking. The European Heart Rhythm Association Scientific Initiatives Committee (EHRA SIC) conducted a survey to explore the current definitions and management of patients with AiCM among European and non-European electrophysiologists.
A 25-item online questionnaire was developed and distributed among EP specialists on the EHRA SIC website and on social media between 4 September and 5 October 2023. Of the 206 respondents, 16% were female and 61% were between 30 and 49 years old. Most of the respondents were EP specialists (81%) working at university hospitals (47%). While most participants (67%) agreed that AiCM should be defined as a left ventricular ejection fraction (LVEF) impairment after new onset of an arrhythmia, only 35% identified a specific LVEF drop to diagnose AiCM with a wide range of values (5-20% LVEF drop). Most respondents considered all available therapies: catheter ablation (93%), electrical cardioversion (83%), antiarrhythmic drugs (76%), and adjuvant HF treatment (76%). A total of 83% of respondents indicated that adjuvant HF treatment should be started at first HF diagnosis prior to antiarrhythmic treatment, and 84% agreed it should be stopped within six months after LVEF normalization. Responses for the optimal time point for the first LVEF reassessment during follow-up varied markedly (1 day-6 months after antiarrhythmic treatment).
This EHRA Survey reveals varying practices regarding AiCM among physicians, highlighting a lack of consensus and heterogenous care of these patients.
心律失常性心肌病(AiCM)是持续性心律失常背景下急性心力衰竭(HF)的一种亚型。目前缺乏对 AiCM 的明确定义和管理建议。欧洲心律协会科学倡议委员会(EHRA SIC)进行了一项调查,以探讨欧洲和非欧洲电生理学家对 AiCM 患者的当前定义和管理。
开发了一个包含 25 个项目的在线问卷,并在 2023 年 9 月 4 日至 10 月 5 日期间在 EHRA SIC 网站和社交媒体上分发给 EP 专家。在 206 名受访者中,16%为女性,61%年龄在 30 至 49 岁之间。大多数受访者(81%)为在大学医院工作的 EP 专家(47%)。虽然大多数参与者(67%)同意 AiCM 应定义为新发生心律失常后左心室射血分数(LVEF)的损害,但只有 35%确定了特定的 LVEF 下降以诊断 AiCM,其范围很广(LVEF 下降 5-20%)。大多数受访者认为所有可用的治疗方法:导管消融(93%)、电复律(83%)、抗心律失常药物(76%)和辅助 HF 治疗(76%)。83%的受访者表示,应在首次 HF 诊断时开始辅助 HF 治疗,然后在 LVEF 正常化后 6 个月内停止治疗,84%的受访者同意应在 LVEF 正常化后 6 个月内停止治疗。在随访期间首次 LVEF 重新评估的最佳时间点的回答差异很大(抗心律失常治疗后 1 天至 6 个月)。
EHRA 调查显示,医生对 AiCM 的治疗方法存在差异,突出了对这些患者缺乏共识和治疗方法不一致的问题。