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双相情感障碍中的认知:给临床医生的最新资讯

Cognition in Bipolar Disorder: An Update for Clinicians.

作者信息

Nicoloro-SantaBarbara Jennifer, Majd Marzieh, Miskowiak Kamilla, Burns Katharine, Goldstein Benjamin I, Burdick Katherine E

机构信息

Department of Psychiatry, Brigham and Women's Hospital, Boston (Nicoloro-SantaBarbara, Majd, Burns, Burdick); Harvard Medical School, Boston (Nicoloro-SantaBarbara, Majd, Burdick); Department of Psychology, University of Copenhagen, and Mental Health Services, Capital Region of Denmark, Copenhagen (Miskowiak); Centre for Addiction and Mental Health, Toronto (Goldstein); and Department of Psychiatry and Department of Pharmacology, University of Toronto, Toronto (Goldstein).

出版信息

Focus (Am Psychiatr Publ). 2023 Oct;21(4):363-369. doi: 10.1176/appi.focus.20230012. Epub 2023 Oct 15.

Abstract

Bipolar disorder is associated with cognitive deficits, which persist across mood states and affect functional outcomes. This article provides an overview of recent progress in measuring cognition in bipolar disorder and its implications for both research and clinical practice. The authors summarize work conducted over the past decade that has helped guide researchers and clinicians in the appropriate measurement of cognitive functioning in bipolar disorder, the design of research studies targeting this domain for treatment, and the implementation of screening and psychoeducational tools in the clinic. Much of this work was conducted by the International Society for Bipolar Disorders Targeting Cognition Task Force. Here, the authors also highlight the need for clinicians to be informed about this aspect of illness and to be equipped with the necessary information to assess, track, and intervene on cognitive problems when appropriate. Finally, the article identifies gaps in the literature and suggests potential future directions for research in this area.

摘要

双相情感障碍与认知缺陷有关,这些缺陷在不同情绪状态下持续存在,并影响功能结局。本文概述了双相情感障碍认知测量的最新进展及其对研究和临床实践的影响。作者总结了过去十年所开展的工作,这些工作有助于指导研究人员和临床医生对双相情感障碍认知功能进行恰当测量、设计针对该领域治疗的研究以及在临床中实施筛查和心理教育工具。这项工作大多是由国际双相情感障碍协会认知靶向特别工作组开展的。在此,作者还强调临床医生需要了解疾病的这一方面,并具备必要信息,以便在适当的时候评估、跟踪和干预认知问题。最后,本文指出了文献中的空白,并提出了该领域未来潜在的研究方向。

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本文引用的文献

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Pramipexole to Improve Cognition in Bipolar Disorder: A Randomized Controlled Trial.
J Clin Psychopharmacol. 2021;41(4):421-427. doi: 10.1097/JCP.0000000000001407.
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Risk of dementia in bipolar disorder and the interplay of lithium: a systematic review and meta-analyses.
Acta Psychiatr Scand. 2020 Jun;141(6):510-521. doi: 10.1111/acps.13153. Epub 2020 Feb 11.
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A Systematic Review of Studies Reporting Data-Driven Cognitive Subtypes across the Psychosis Spectrum.
Neuropsychol Rev. 2020 Dec;30(4):446-460. doi: 10.1007/s11065-019-09422-7. Epub 2019 Dec 18.
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C-reactive protein is associated with cognitive performance in a large cohort of euthymic patients with bipolar disorder.
Mol Psychiatry. 2021 Aug;26(8):4096-4105. doi: 10.1038/s41380-019-0591-1. Epub 2019 Nov 19.

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