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埃塞俄比亚的化疗安全操作规范:一项全面的多中心评估。

Chemotherapy safe handling practices in Ethiopia: A comprehensive multi-center evaluation.

作者信息

Webb Nathaniel, Matys Samantha, Collins James B, Garcia Julian, Worku Kaleab, Lines Mandee, Hirata Hailey, Dark Erin, Brooks Callee, Buhlinger Kaitlyn, Fentie Atalay Mulu, Roberts Megan C, Muluneh Benyam

机构信息

Department of Health Policy and Management, UNC Gillings School of Global Public Health, Chapel Hill, NC, USA.

UNC Eshelman School of Pharmacy, Chapel Hill, NC, USA.

出版信息

J Oncol Pharm Pract. 2025 Jun;31(4):597-607. doi: 10.1177/10781552241249420. Epub 2024 May 2.

Abstract

IntroductionThe increasing incidence of cancer and capacity for cancer care in Ethiopia has led to an upsurge in chemotherapy use in the country; however, studies indicate that there is a gap in the safe handling of chemotherapy by healthcare workers. There exists a need to understand if such unsafe practices occur in Ethiopia and, if so, which areas along the chemotherapy life cycle need the most improvement.MethodsThis study utilized a multi-method design through an online survey administered to health care professionals and evaluative site visits of eight cancer units in Addis Ababa, Ethiopia to understand the current conditions of chemotherapy handling. In addition, a survey was conducted among Ethiopian health care professionals from across the country.ResultsFifty-five percent of survey participants disagreed or strongly disagreed that there are systems in place to identify, prevent, and address chemotherapy hazards in their workplace, and 71% of respondents denied having an active and effective health and safety committee and/or worker health and safety representative where they work. At evaluative site visits, only 30% of health care workers met the minimum guidelines for proper hand hygiene, and 20% of health care workers used adequate Personal Protective Equipment according to guidelines across the chemotherapy lifecycle.ConclusionsResults of this study indicate an urgent need for implementation of evidence-based interventions to improve chemotherapy handling in Ethiopia so that all patients and health care workers are protected from the hazardous toxicities of these drugs.

摘要

引言

埃塞俄比亚癌症发病率的上升以及癌症护理能力的提升导致该国化疗使用量激增;然而,研究表明医护人员在化疗安全处理方面存在差距。有必要了解此类不安全做法在埃塞俄比亚是否存在,若存在,化疗生命周期中的哪些环节最需要改进。

方法

本研究采用多方法设计,通过对医护人员进行在线调查以及对埃塞俄比亚亚的斯亚贝巴的八个癌症治疗单位进行评估性实地考察,以了解化疗处理的现状。此外,还对来自埃塞俄比亚全国的医护人员进行了一项调查。

结果

55%的调查参与者不同意或强烈不同意其工作场所存在识别、预防和应对化疗危害的系统,71%的受访者否认其工作场所设有活跃且有效的健康与安全委员会和/或工人健康与安全代表。在评估性实地考察中,只有30%的医护人员达到了正确手部卫生的最低标准,20%的医护人员在整个化疗生命周期中按照指南使用了足够的个人防护装备。

结论

本研究结果表明,迫切需要实施基于证据的干预措施,以改善埃塞俄比亚的化疗处理情况,从而保护所有患者和医护人员免受这些药物的有害毒性影响。

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