Emory University, Nell Hodgson Woodruff School of Nursing, Atlanta, GA.
Office of Nursing Research; Emory University, Nell Hodgson Woodruff School of Nursing, Atlanta, GA.
Pain Manag Nurs. 2024 Aug;25(4):425-431. doi: 10.1016/j.pmn.2024.04.007. Epub 2024 May 1.
This study assessed the feasibility of an in-home virtual reality intervention for chronic pain in adults with sickle cell disease.
Two-group, parallel, randomized, multiple methods design with surveys, and interviews.
Participants were randomized to virtual reality or audio control, with 2-16-minute daily modules for 8 weeks, a daily pain diary survey, and a post study interview. Chronic pain and pain correlates were evaluated at baseline and every 4 weeks for 3 months. Feasibility outcomes were participant enrollment (set at > 50%), questionnaire response (> 50%), intervention use, and cybersickness (< 20%).
Of the individuals approached, 67.8% (n = 19) were enrolled. Questionnaire response rates were 100% at baseline, 57.8% at week 4, and < 50% at weeks 8 and 12. The intervention was used for a median of 781 minutes and 210 minutes in the virtual reality and audio groups, respectively. Participants reported slight symptoms of cybersickness with no reports of severe symptoms, and the intervention was acceptable.
Home-based virtual reality can be used in future sickle cell disease research. To further strengthen evaluations of virtual reality in adults with sickle cell who experience chronic pain, future trials should address sample size limitations and incorporate recommended strategies to address cybersickness and questionnaire response.
The first known application of in-home virtual reality for chronic pain in adults with sickle cell disease was successful. Findings can inform future in-home investigations of virtual reality in this underserved population.
本研究评估了一种针对成人镰状细胞病慢性疼痛的家庭虚拟实境干预的可行性。
两组平行随机对照的多方法设计，包括问卷调查和访谈。
参与者随机分为虚拟现实组或音频对照组，每天接受 2-16 分钟的模块，共 8 周，每日疼痛日记调查和研究后访谈。在基线和 3 个月内每 4 周评估慢性疼痛和疼痛相关性。可行性结果包括参与者入组（>50%）、问卷应答率（>50%）、干预使用情况和网络眩晕（<20%）。
在接触的人群中，67.8%（n=19）入组。基线时问卷应答率为 100%，第 4 周为 57.8%，第 8 周和第 12 周<50%。虚拟现实组和音频组的干预平均使用时间分别为 781 分钟和 210 分钟。参与者报告有轻微的网络眩晕症状，但无严重症状报告，且干预可接受。
家庭虚拟实境可用于未来的镰状细胞病研究。为了进一步加强对慢性疼痛成人镰状细胞病患者虚拟实境的评估，未来的试验应解决样本量限制，并采用建议策略解决网络眩晕和问卷应答问题。
首次成功应用家庭虚拟实境治疗成人镰状细胞病慢性疼痛。研究结果可为未来在这一服务不足人群中开展家庭虚拟实境调查提供信息。
