Faculty of Health Sciences, Universidad Icesi, Cali, Colombia.
Department of Internal Medicine, Allergology Service, Fundación Valle del Lili, Cali, Colombia.
Chron Respir Dis. 2024 Jan-Dec;21:14799731241251827. doi: 10.1177/14799731241251827.
Asthma and obstructive sleep apnea (OSA) are common respiratory disorders. They share characteristics such as airway obstruction, poor sleep quality, and low quality of life. They are often present as comorbidities, along with obesity, gastroesophageal reflux disease (GERD), and allergic rhinitis (AR), which impacts the disease's control. In recent years, there has been discussion about the association between these conditions and their pathophysiological and clinical consequences, resulting in worse health outcomes, increased healthcare resource consumption, prolonged hospital stays, and increased morbidity and mortality. Some studies demonstrate that treatment with continuous positive airway pressure (CPAP) can have a beneficial effect on both pathologies. This review summarizes the existing evidence of the association between asthma and OSA at their pathophysiological, epidemiological, clinical, and therapeutic levels. It intends to raise awareness among healthcare professionals about these conditions and the need for further research.
哮喘和阻塞性睡眠呼吸暂停（OSA）是常见的呼吸系统疾病。它们具有气道阻塞、睡眠质量差和生活质量低等共同特征。它们常作为共病存在，同时还伴有肥胖、胃食管反流病（GERD）和过敏性鼻炎（AR），这会影响疾病的控制。近年来，人们一直在讨论这些疾病之间的关联及其病理生理和临床后果，导致健康状况恶化、医疗资源消耗增加、住院时间延长以及发病率和死亡率增加。一些研究表明，持续气道正压通气（CPAP）治疗对这两种疾病都有有益的效果。本综述总结了哮喘和 OSA 在病理生理、流行病学、临床和治疗方面的关联的现有证据。它旨在提高医疗保健专业人员对这些疾病的认识，并需要进一步研究。
