• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Physiological Integration of Taste and Metabolism.

作者信息

Egan Josephine M

机构信息

From the Diabetes Section, Laboratory of Clinical Investigation, National Institute on Aging, National Institutes of Health, Baltimore.

出版信息

N Engl J Med. 2024 May 9;390(18):1699-1710. doi: 10.1056/NEJMra2304578.

DOI:10.1056/NEJMra2304578
PMID:38718360
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12076092/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d9de/12076092/c63e7e9e2ebb/nihms-2077413-f0004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d9de/12076092/5046d1a9c14c/nihms-2077413-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d9de/12076092/c3809f986869/nihms-2077413-f0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d9de/12076092/9a5033e1d679/nihms-2077413-f0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d9de/12076092/c63e7e9e2ebb/nihms-2077413-f0004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d9de/12076092/5046d1a9c14c/nihms-2077413-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d9de/12076092/c3809f986869/nihms-2077413-f0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d9de/12076092/9a5033e1d679/nihms-2077413-f0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d9de/12076092/c63e7e9e2ebb/nihms-2077413-f0004.jpg

相似文献

1
Physiological Integration of Taste and Metabolism.味觉与新陈代谢的生理整合
N Engl J Med. 2024 May 9;390(18):1699-1710. doi: 10.1056/NEJMra2304578.
2
What is the role of metabolic hormones in taste buds of the tongue.代谢激素在舌味蕾中起什么作用？
Front Horm Res. 2014;42:134-46. doi: 10.1159/000358322. Epub 2014 Apr 7.
3
Hedgehog Signaling Regulates Taste Organs and Oral Sensation: Distinctive Roles in the Epithelium, Stroma, and Innervation.刺猬信号通路调控味觉器官和口腔感觉：在上皮组织、基质组织和神经支配中具有独特的作用。
Int J Mol Sci. 2019 Mar 16;20(6):1341. doi: 10.3390/ijms20061341.
4
Molecular mechanisms of taste transduction in vertebrates.脊椎动物味觉转导的分子机制。
Odontology. 2009 Jan;97(1):1-7. doi: 10.1007/s10266-008-0095-y. Epub 2009 Jan 29.
5
Gustatory system: the finer points of taste.味觉系统：味觉的精妙之处。
Nature. 2012 Jun 20;486(7403):S2-3. doi: 10.1038/486S2a.
6
Morphological and biochemical heterogeneity in facial and vagal nerve innervated taste buds of the channel catfish, Ictalurus punctatus.斑点叉尾鮰面神经和迷走神经支配味蕾的形态学与生化异质性
J Comp Neurol. 2005 May 30;486(2):132-44. doi: 10.1002/cne.20543.
7
Glucagon-Like Peptide 1 and Taste Perception: From Molecular Mechanisms to Potential Clinical Implications.胰高血糖素样肽 1 与味觉感知：从分子机制到潜在的临床意义。
Int J Mol Sci. 2021 Jan 18;22(2):902. doi: 10.3390/ijms22020902.
8
Metabotropic glutamate receptor type 1 in taste tissue.味觉组织中的代谢型谷氨酸受体1
Am J Clin Nutr. 2009 Sep;90(3):743S-746S. doi: 10.3945/ajcn.2009.27462I. Epub 2009 Jul 1.
9
[Electrogustometry].[电味觉测试]
Otolaryngol Pol. 1972;26(2):229-35.
10
The endocrinology of taste receptors.味觉受体的内分泌学。
Nat Rev Endocrinol. 2015 Apr;11(4):213-27. doi: 10.1038/nrendo.2015.7. Epub 2015 Feb 24.

引用本文的文献

1
Functional variants in the TAS2R38 bitter taste receptor associate with postprandial glycemia.味觉受体TAS2R38中的功能性变异与餐后血糖相关。
medRxiv. 2025 May 23:2025.05.23.25328232. doi: 10.1101/2025.05.23.25328232.
2
From Liking to Following: The Role of Food Preferences, Taste Perception, and Lifestyle Factors in Adherence to the Mediterranean Diet Among Young Individuals.从喜爱到遵循：食物偏好、味觉感知和生活方式因素在年轻人坚持地中海饮食中的作用
Nutrients. 2025 Feb 6;17(3):600. doi: 10.3390/nu17030600.
3
Differences in Perceived Versus Actual Sensory Perception in Avoidant/Restrictive Food Intake Disorder.

本文引用的文献

1
Persistent symptoms are associated with long term effects of COVID-19 among children and young people: Results from a systematic review and meta-analysis of controlled studies.持续性症状与儿童和青少年 COVID-19 的长期影响有关：一项系统评价和对照研究荟萃分析的结果。
PLoS One. 2023 Dec 28;18(12):e0293600. doi: 10.1371/journal.pone.0293600. eCollection 2023.
2
Long-Term Dysfunction of Taste Papillae in SARS-CoV-2.新型冠状病毒感染中味觉乳头的长期功能障碍
NEJM Evid. 2023 Sep;2(9). doi: 10.1056/evidoa2300046. Epub 2023 Jul 20.
3
The proton channel OTOP1 is a sensor for the taste of ammonium chloride.
回避/限制性食物摄入障碍中感知到的与实际感觉知觉的差异。
Int J Eat Disord. 2025 Apr;58(4):703-713. doi: 10.1002/eat.24358. Epub 2025 Jan 17.
4
Olfactory and gustatory perception in Brazilian PKU patients: A cross-sectional study.巴西苯丙酮尿症患者的嗅觉和味觉感知：一项横断面研究。
JIMD Rep. 2024 Aug 29;65(6):426-432. doi: 10.1002/jmd2.12445. eCollection 2024 Nov.
5
Effect of a Novel Food Rich in Miraculin on the Oral Microbiome of Malnourished Oncologic Patients with Dysgeusia.一种富含奇果蛋白的新型食物对患有味觉障碍的营养不良肿瘤患者口腔微生物群的影响。
Cancers (Basel). 2024 Oct 8;16(19):3414. doi: 10.3390/cancers16193414.
6
GLP-1 single, dual, and triple receptor agonists for treating type 2 diabetes and obesity: a narrative review.用于治疗2型糖尿病和肥胖症的GLP-1单受体、双受体和三受体激动剂：一项叙述性综述
EClinicalMedicine. 2024 Aug 30;75:102782. doi: 10.1016/j.eclinm.2024.102782. eCollection 2024 Sep.
质子通道 OTOP1 是氯化铵味觉的感受器。
Nat Commun. 2023 Oct 5;14(1):6194. doi: 10.1038/s41467-023-41637-4.
4
Endocrinology of Taste with Aging.味觉的内分泌变化与衰老
Endocrinol Metab Clin North Am. 2023 Jun;52(2):295-315. doi: 10.1016/j.ecl.2022.10.002. Epub 2023 Feb 16.
5
The dietary sweetener sucralose is a negative modulator of T cell-mediated responses.食用甜味剂三氯蔗糖是 T 细胞介导的反应的负调节剂。
Nature. 2023 Mar;615(7953):705-711. doi: 10.1038/s41586-023-05801-6. Epub 2023 Mar 15.
6
Chloride ions evoke taste sensations by binding to the extracellular ligand-binding domain of sweet/umami taste receptors.氯离子通过与甜/鲜味味觉受体的细胞外配体结合域结合来引发味觉感受。
Elife. 2023 Feb 28;12:e84291. doi: 10.7554/eLife.84291.
7
The artificial sweetener erythritol and cardiovascular event risk.人工甜味剂赤藓糖醇与心血管事件风险。
Nat Med. 2023 Mar;29(3):710-718. doi: 10.1038/s41591-023-02223-9. Epub 2023 Feb 27.
8
Physiology of the tongue with emphasis on taste transduction.舌生理学，重点介绍味觉转导。
Physiol Rev. 2023 Apr 1;103(2):1193-1246. doi: 10.1152/physrev.00012.2022. Epub 2022 Nov 24.
9
Trends in added sugars intake and sources among U.S. adults using the National Health and Nutrition Examination Survey (NHANES) 2001-2018.利用2001 - 2018年美国国家健康与营养检查调查（NHANES）分析美国成年人添加糖摄入量及来源的趋势。
Front Nutr. 2022 Aug 18;9:897952. doi: 10.3389/fnut.2022.897952. eCollection 2022.
10
Personalized microbiome-driven effects of non-nutritive sweeteners on human glucose tolerance.非营养性甜味剂对人体葡萄糖耐量的个性化微生物群驱动效应。
Cell. 2022 Sep 1;185(18):3307-3328.e19. doi: 10.1016/j.cell.2022.07.016. Epub 2022 Aug 19.