Peanut agglutinin, a marker for T-cell acute lymphoblastic leukemia with a good prognosis.
作者信息
Veerman A J, Hogeman P H, Huismans D R, Van Zantwijk C H, Bezemer P D
出版信息
Cancer Res. 1985 Apr;45(4):1890-3.
PMID:3872169
Abstract
Peanut agglutinin (PNA) binding was studied in cells from 74 children with acute lymphoblastic leukemia (ALL). PNA positivity occurred in 50% of T-ALL (12 of 24) and was rare in other types of ALL. There was no clear relationship between PNA and initial white blood cell count, French-American-British classification, stage of differentiation of leukemic cells, hand mirror cells, and organomegaly at diagnosis. Prognosis, however, was significantly better (continuous complete remission, death) in the PNA-positive T-ALLs. It seems that PNA is a useful marker for a subgroup of T-ALL with a better prognosis.
摘要
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