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夸祖鲁-纳塔尔省伊伦贝低社会经济社区老年人痴呆症及相关因素筛查

Screening for dementia and associated factors in older adults from low socioeconomic communities in iLembe, KwaZulu-Natal.

作者信息

Mfene Xoli P, Pillay Basil J

机构信息

Department of Psychology, Faculty of Applied Human Sciences, University of KwaZulu Natal, Pietermaritzburg, South Africa.

Department of Behavioural Medicine, Faculty of Nursing and Public Health, University of KwaZulu Natal, Durban, South Africa.

出版信息

Health SA. 2024 Apr 12;29:2437. doi: 10.4102/hsag.v29i0.2437. eCollection 2024.

Abstract

BACKGROUND

Dementia is one of the leading non-communicable causes of disability and mortality in older adults, with recent research showing that it is increasing in low-middle-income countries compared to high-income countries. As such, multidisciplinary efforts are needed to effectively reduce the prevalence and risk of dementia through quick screening, diagnosis, and management of those with dementia and those at risk.

AIM

The study's objectives were to estimate the prevalence of dementia and measure the sociodemographic and clinical risks in older adults in low socioeconomic communities.

SETTING

The study was conducted among older adults aged ≥ 60 years from the iLembe district in South Africa.

METHODS

This cross-sectional, one-phased, household study was conducted to screen for dementia over 8 months between October 2018 and October 2019. Demographic and clinical data were collected using a semi-structured questionnaire. In addition, the Mini-Mental Status Exam, Ascertain Dementia Eight-item questionnaire and Instrumental Activities of Daily Living Scale were administered to a multi-stage cluster sample of 320 participants to ascertain dementia prevalence. Frequencies and multivariate logistic regression were conducted to determine risk factors correlated with dementia.

RESULTS

The prevalence of dementia was 13.4%. Participants aged 80 years and above were 2.73 times more likely to develop dementia than participants younger than 80 years. Those with an education level of Grade 1-7 had a 69% less chance of developing dementia than those without formal education. Single participants showed an almost seven-fold increase in dementia. Lastly, depression increased the risk of dementia by two-fold.

CONCLUSION

Dementia was probable in over one-sixth of the sample. Dementia risk factors were both modifiable and non-modifiable.

CONTRIBUTION

Dementia prevalence in South Africa is increasing and therefore it is crucial to develop a dementia plan that is specific to the South African context which will include strategies for early identification of the disease, reducing modifiable risks and strategic management of dementia associated medical conditions such as depression and vascular diseases.

摘要

背景

痴呆症是老年人致残和致死的主要非传染性病因之一,最近的研究表明,与高收入国家相比,中低收入国家的痴呆症发病率正在上升。因此,需要多学科努力,通过对痴呆症患者和高危人群进行快速筛查、诊断和管理,有效降低痴呆症的患病率和风险。

目的

该研究的目的是估计低社会经济社区老年人痴呆症的患病率,并衡量其社会人口统计学和临床风险。

地点

该研究在南非伊莱姆贝区60岁及以上的老年人中进行。

方法

这项横断面、单阶段的家庭研究于2018年10月至2019年10月的8个月内进行,以筛查痴呆症。使用半结构化问卷收集人口统计学和临床数据。此外,对320名参与者的多阶段整群样本进行简易精神状态检查、痴呆症八项确诊问卷和日常生活活动能力量表测试,以确定痴呆症患病率。进行频率分析和多变量逻辑回归,以确定与痴呆症相关的风险因素。

结果

痴呆症的患病率为13.4%。80岁及以上的参与者患痴呆症的可能性是80岁以下参与者的2.73倍。教育水平为1-7年级的参与者患痴呆症的可能性比未受过正规教育的参与者低69%。单身参与者患痴呆症的几率几乎增加了七倍。最后,抑郁症使患痴呆症的风险增加了两倍。

结论

超过六分之一的样本可能患有痴呆症。痴呆症的风险因素既有可改变的,也有不可改变的。

贡献

南非痴呆症的患病率正在上升,因此制定一项针对南非情况的痴呆症计划至关重要,该计划将包括疾病早期识别策略、降低可改变的风险以及对与痴呆症相关的医疗状况(如抑郁症和血管疾病)进行战略管理。

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