Lewis M, Kallenbach J, Ruff P, Zaltzman M, Abramowitz J, Zwi S
Chest. 1985 May;87(5):691-3. doi: 10.1378/chest.87.5.691.
A rare occurrence of invasive pulmonary aspergillosis complicates influenza pneumonia in a previously healthy adult. Five other similar cases are reported in the literature. Both transient depression of cell-mediated immunity and loss of ciliary function in the tracheobronchial tree occurs during acute influenzal illness and may predispose to fungal superinfection. Early diagnosis and treatment of opportunistic Aspergillus infection complicating influenza is mandatory in view of the high mortality associated with this complication.
一名既往健康的成年人患流感肺炎后并发罕见的侵袭性肺曲霉病。文献中还报道了其他5例类似病例。在急性流感疾病期间,细胞介导的免疫功能会出现短暂抑制,气管支气管树的纤毛功能也会丧失,这可能易引发真菌二重感染。鉴于这种并发症的高死亡率,对于流感并发的机会性曲霉感染进行早期诊断和治疗至关重要。