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与流感相关的侵袭性肺曲霉病

Invasive pulmonary aspergillosis associated with influenza.

作者信息

Fischer J J, Walker D H

出版信息

JAMA. 1979 Apr 6;241(14):1493-4.

PMID:372590
Abstract

Fatal invasive pulmonary aspergillosis may follow viral influenza infections. Two cases with verified influenza A infection were followed by fatal necrotizing pneumonia due to Aspergillus fumigatus. Both patients demonstrated cutaneous anergy and lymphocytopenia. Influenza and perhaps other viruses that depress T-cell function may result in increased susceptibility to infections in which T cells are important in host defenses.

摘要

致命性侵袭性肺曲霉病可能继发于病毒性流感感染。两例确诊为甲型流感感染的患者随后因烟曲霉导致了致命性坏死性肺炎。两名患者均表现为皮肤无反应性和淋巴细胞减少。流感以及其他可能抑制T细胞功能的病毒,可能会导致机体对某些感染的易感性增加,而在这些感染中T细胞对宿主防御起着重要作用。

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