Integrative Oncology Program, The Oncology Service, Zebulun Medical Centers, Clalit Health Services, Haifa and Western Galilee District, Carmel &, Lin, Israel.
Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel.
Curr Oncol Rep. 2024 Jun;26(6):714-734. doi: 10.1007/s11912-024-01538-1. Epub 2024 May 11.
Children and adolescents with cancer, along with their parents and other informal caregivers, often report using complementary and alternative medicine (CAM) during active oncology and hemato-oncology treatment. Some adopt an "alternative" approach to conventional medical care, which often entails the use of these practices without the knowledge of the treating pediatrician. In contrast, many others search for consultation provided by a pediatric integrative oncology (IO) practitioner working with the conventional medical team. IO seeks to provide evidence-based complementary medicine therapies, many of which have been shown to augment conventional supportive and palliative care, while ensuring the patient's safety. The present narrative review examines the current state of and future direction for the IO setting of care.
A large body of published clinical research supports the effectiveness of leading Pediatric IO modalities, while addressing potential safety-related concerns. Despite the growing amount of clinical research supporting the beneficial effects and implementation of Pediatric IO models of care, there is still a need for further studies in order to establish clinical guidelines in the treatment of children and adolescents with cancer. Such IO-directed guidelines will need to address both the effectiveness and the safety of the CAM modalities being used in pediatric oncology and hemato-oncology settings, promoting a better understanding among pediatric healthcare professionals and helping them understand the indications for referral to the IO treatment service.
癌症患儿及其父母和其他非正式照护者在积极进行肿瘤学和血液肿瘤学治疗期间，常报告采用补充和替代医学（CAM）。一些人对常规医疗护理采取“替代”方法，这通常涉及在未经主治儿科医生知情的情况下使用这些疗法。相比之下，许多人则寻求与常规医疗团队合作的儿科综合肿瘤学（IO）从业者提供的咨询。IO 旨在提供循证补充医学疗法，其中许多疗法已被证明可增强常规支持和姑息治疗，同时确保患者安全。本叙述性综述检查了 IO 护理设置的现状和未来方向。
大量已发表的临床研究支持主要儿科 IO 疗法的有效性，同时解决了潜在的与安全相关的问题。尽管越来越多的临床研究支持对儿科 IO 护理模式的有益效果和实施，但仍需要进一步研究以制定儿童和青少年癌症治疗的临床指南。此类 IO 指导方针将需要解决在儿科肿瘤学和血液肿瘤学环境中使用的 CAM 疗法的有效性和安全性，以增进儿科医疗保健专业人员的理解，并帮助他们了解向 IO 治疗服务转诊的适应症。
