鼠伤寒沙门氏菌hisG基因的精细图谱。
A refined map of the hisG gene of Salmonella typhimurium.
作者信息
Hoppe I, Johnston H M, Biek D, Roth J R
出版信息
Genetics. 1979 May;92(1):17-26. doi: 10.1093/genetics/92.1.17.
Abstract
The hisG gene is the most operator-proximal structural gene of the histidine operon; it encodes the feedback-inhibitable first enzyme of the biosynthetic pathway. Previously, hisG mutants were mapped into seven intervals defined by the availble deletion mutations having endpoints in the hisG gene. The map has been refined using over 60 new deletion mutants. The new map divides the gene into 40 deletion intervals, which average approximately 30 base pairs in length. The map has been used to analyze the distribution of insertion sites for the transposable element Tn10 and has permitted conclusions on the diistribution of duplication endpoints. The map promises to be useful in analysis of his regulation and, more particularly, in the determination of the possible role of the hisG enzyme in this mechanism.
摘要
hisG基因是组氨酸操纵子中最靠近操纵基因的结构基因；它编码生物合成途径中可被反馈抑制的第一种酶。以前，hisG突变体被定位到由hisG基因中具有端点的可用缺失突变所定义的七个区间。利用60多个新的缺失突变体对该图谱进行了完善。新图谱将该基因分为40个缺失区间，平均长度约为30个碱基对。该图谱已用于分析转座因子Tn10插入位点的分布，并得出了重复端点分布的结论。该图谱有望在his调控分析中发挥作用，更具体地说，在确定hisG酶在该机制中可能发挥的作用方面发挥作用。
相似文献
1
A refined map of the hisG gene of Salmonella typhimurium.鼠伤寒沙门氏菌hisG基因的精细图谱。
Genetics. 1979 May;92(1):17-26. doi: 10.1093/genetics/92.1.17.
2
Histidine mutants requiring adenine: selection of mutants with reduced hisG expression in Salmonella typhimurium.需要腺嘌呤的组氨酸突变体：鼠伤寒沙门氏菌中组氨酸G表达降低的突变体筛选
Genetics. 1979 May;92(1):1-15. doi: 10.1093/genetics/92.1.1.
3
Phenotypic and reversion analysis of a Salmonella typhimurium constructed to have an arginine codon at the hisG46 missense codon.
Mutat Res. 1988 Sep;201(1):189-94. doi: 10.1016/0027-5107(88)90125-x.
4
Regulation of the histidine operon: translation-controlled transcription termination (a mechanism common to several biosynthetic operons).组氨酸操纵子的调控：翻译控制的转录终止（一种存在于多个生物合成操纵子中的机制）。
Curr Top Cell Regul. 1981;19:1-45. doi: 10.1016/b978-0-12-152819-5.50018-x.
5
Specific binding of the first enzyme for histidine biosynthesis to the DNA of histidine operon.参与组氨酸生物合成的第一种酶与组氨酸操纵子DNA的特异性结合。
Nucleic Acids Res. 1975 Nov;2(11):2021-36. doi: 10.1093/nar/2.11.2021.
6
The amino terminal sequence of ATP-phosphoribosyltransferase, the first gene product of the histidine operon.组氨酸操纵子的首个基因产物——ATP-磷酸核糖基转移酶的氨基末端序列。
Biochem Biophys Res Commun. 1977 Sep 23;78(2):833-8. doi: 10.1016/0006-291x(77)90255-8.
7
Regulation of histidine operon does not require hisG enzyme.组氨酸操纵子的调控不需要hisG酶。
Proc Natl Acad Sci U S A. 1975 Dec;72(12):5021-5. doi: 10.1073/pnas.72.12.5021.
8
trans-Recessive mutation in the first structural gene of the histidine operon that results in constitutive expression of the operon.组氨酸操纵子第一个结构基因中的反式隐性突变，导致该操纵子组成型表达。
J Bacteriol. 1975 Dec;124(3):1227-35. doi: 10.1128/jb.124.3.1227-1235.1975.
9
Transcriptional occlusion of transposon targets.转座子靶标的转录阻碍
Mol Gen Genet. 1989 Apr;216(2-3):204-9. doi: 10.1007/BF00334357.
10
引用本文的文献
1
Specific features of L-histidine production by Escherichia coli concerned with feedback control of AICAR formation and inorganic phosphate/metal transport.大肠杆菌 L-组氨酸生产的特定特征与 AICAR 形成和无机磷酸盐/金属运输的反馈控制有关。
Microb Cell Fact. 2018 Mar 15;17(1):42. doi: 10.1186/s12934-018-0890-2.
2
Biosynthesis of Histidine.组氨酸的生物合成
EcoSal Plus. 2009 Aug;3(2). doi: 10.1128/ecosalplus.3.6.1.9.
3
Recombination in the Vicinity of Insertions of Transposon Tn 5 in MYXOCOCCUS XANTHUS.转座子 Tn5 在黄原胶菌插入位点附近的重组。
Genetics. 1983 Oct;105(2):281-91. doi: 10.1093/genetics/105.2.281.
4
Histidine biosynthetic pathway and genes: structure, regulation, and evolution.组氨酸生物合成途径与基因：结构、调控及进化
Microbiol Rev. 1996 Mar;60(1):44-69. doi: 10.1128/mr.60.1.44-69.1996.
5
Proline over-production results in enhanced osmotolerance in Salmonella typhimurium.脯氨酸过量产生可增强鼠伤寒沙门氏菌的渗透压耐受性。
Mol Gen Genet. 1981;182(1):82-6. doi: 10.1007/BF00422771.
6
Infection of Salmonella typhimurium with coliphage Mu d1 (Apr lac): construction of pyr::lac gene fusions.用大肠杆菌噬菌体Mu d1（Apr lac）感染鼠伤寒沙门氏菌：构建pyr::lac基因融合体。
J Bacteriol. 1981 Jan;145(1):299-305. doi: 10.1128/jb.145.1.299-305.1981.
7
Genetic mapping of IS200 copies in Salmonella typhimurim strain LT2.鼠伤寒沙门氏菌LT2菌株中IS200拷贝的基因定位。
Genetics. 1983 Dec;105(4):801-11. doi: 10.1093/genetics/105.4.801.
8
Linkage map of Salmonella typhimurium, Edition VI.鼠伤寒沙门氏菌连锁图谱，第六版。
Microbiol Rev. 1983 Sep;47(3):410-53. doi: 10.1128/mr.47.3.410-453.1983.
9
DNA sequences at the sites of three insertions of the transposable element Tn5 in the histidine operon of Salmonella.沙门氏菌组氨酸操纵子中可转座元件Tn5的三个插入位点处的DNA序列。
Mol Gen Genet. 1981;183(2):406-8. doi: 10.1007/BF00270649.
10
Cloning and restriction map of the first part of the histidine operon of Salmonella typhimurium.鼠伤寒沙门氏菌组氨酸操纵子第一部分的克隆与限制酶图谱
J Bacteriol. 1981 Jul;147(1):124-34. doi: 10.1128/jb.147.1.124-134.1981.
本文引用的文献
1
Acetylornithinase of Escherichia coli: partial purification and some properties.大肠杆菌的乙酰鸟氨酸酶：部分纯化及某些性质
J Biol Chem. 1956 Jan;218(1):97-106.
2
3
Mutations creating a new initiation point for expression of the histidine operon in Salmonella typhimurium.在鼠伤寒沙门氏菌中产生组氨酸操纵子表达新起始点的突变。
J Mol Biol. 1968 Jul 14;35(1):71-82. doi: 10.1016/s0022-2836(68)80037-3.
4
Proflavin mutagenesis of bacteria.细菌的原黄素诱变
J Mol Biol. 1974 Oct 15;89(1):17-32. doi: 10.1016/0022-2836(74)90160-0.
5
Multiple aggregation states of phosphoribosyladenosine triphosphate synthetase.
J Biol Chem. 1974 Jul 10;249(13):4119-26.
6
Characterization of slowly interconvertible states of phosphoribosyladenosine triphosphate synthetase dependent on temperature, substrates, and histidine.
J Biol Chem. 1974 Jul 10;249(13):4110-8.
7
Regulation of histidine operon does not require hisG enzyme.组氨酸操纵子的调控不需要hisG酶。
Proc Natl Acad Sci U S A. 1975 Dec;72(12):5021-5. doi: 10.1073/pnas.72.12.5021.
8
Evidence that mutations in the suA polarity suppressing gene directly affect termination factor rho.suA极性抑制基因中的突变直接影响终止因子rho的证据。
Nature. 1976 Jan 15;259(5539):151-3. doi: 10.1038/259151a0.
9
trans-Recessive mutation in the first structural gene of the histidine operon that results in constitutive expression of the operon.组氨酸操纵子第一个结构基因中的反式隐性突变，导致该操纵子组成型表达。
J Bacteriol. 1975 Dec;124(3):1227-35. doi: 10.1128/jb.124.3.1227-1235.1975.
10
Mutagenesis by insertion of a drug-resistance element carrying an inverted repetition.通过插入携带反向重复序列的耐药元件进行诱变。
J Mol Biol. 1975 Oct 5;97(4):561-75. doi: 10.1016/s0022-2836(75)80059-3.
Zotero 插件