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评估尼日利亚5岁以下儿童看护者接受疟疾疫苗的知识、态度、认知及意愿。

Evaluating the knowledge, attitude, perception, and readiness of caregivers of under 5-year-old children to accept malaria vaccine in Nigeria.

作者信息

Emmanuel Blessing Nkechi, Ishaq Abubakar Nuhu, Akunne Olisaemeka Zikora, Saidu Umar Faruk

机构信息

Department of Zoology, Faculty of Life Sciences, Modibbo Adama University of Technology, Yola, Nigeria.

Department of Biology, Faculty of Life Sciences, Ahmadu Bello University, Zaria, Nigeria.

出版信息

Clin Exp Vaccine Res. 2024 Apr;13(2):121-131. doi: 10.7774/cevr.2024.13.2.121. Epub 2024 Apr 30.

Abstract

PURPOSE

The global burden of disease and mortality is greatly influenced by malaria, particularly in children. Nigeria alone accounts for about 25% of global malaria cases and fatalities. Despite efforts to control and eliminate malaria, conventional treatments have limitations, prompting the need for a vaccine. However, while efforts have focused on researching and developing malaria vaccines, less attention has been given to public acceptance and preparedness for vaccination.

MATERIALS AND METHODS

The study employed a cross-sectional approach to assess the knowledge, perceptions, and readiness of caregivers towards the malaria vaccine. Data were collected through a physical and online survey among a representative sample of caregivers across the six geopolitical regions of Nigeria. The data was analyzed using principal component analysis and percentages.

RESULTS

Out of 347 respondents, 180 (51%) men, 165 (46.6%) women, 2 (0.5%) transgender, 156 (45%) rural settlers, and 191 (55%) urban settlers were identified in this study. The study reported an overall acceptance rate of 78.4% and 21.6% resistance rate. The age group between 21-30 years recorded the highest 207 (59.6%). A significant number of participants, 252 (59.6%), held at least a higher or post-secondary certificate, out of which 193 (55.6%) demonstrated strong readiness to accept the malaria vaccine. The study showed that fear of adverse effects was the main reason for malaria vaccine resistance among caregivers.

CONCLUSION

This study's findings offer valuable insights into caregivers' knowledge about the malaria vaccine, highlighting the factors that impact the acceptance of the malaria vaccine.

摘要

目的

疟疾对全球疾病负担和死亡率有重大影响,尤其是对儿童。仅尼日利亚就占全球疟疾病例和死亡人数的约25%。尽管为控制和消除疟疾做出了努力,但传统治疗方法存在局限性,这促使人们需要一种疫苗。然而,虽然一直在努力研究和开发疟疾疫苗,但对公众对疫苗接种的接受度和准备情况关注较少。

材料与方法

本研究采用横断面研究方法,评估照顾者对疟疾疫苗的知识、认知和接种意愿。通过对尼日利亚六个地缘政治区域的照顾者代表性样本进行实地和在线调查收集数据。使用主成分分析和百分比对数据进行分析。

结果

在347名受访者中,本研究确定有180名(51%)男性、165名(46.6%)女性、2名(0.5%)跨性别者、156名(45%)农村居民和191名(55%)城市居民。该研究报告总体接受率为78.4%,抗拒率为21.6%。21至30岁年龄组的接受率最高,为207人(59.6%)。相当数量的参与者,即252人(59.6%)至少拥有高等或大专学历,其中193人(55.6%)表现出强烈的接种疟疾疫苗的意愿。研究表明,担心不良反应是照顾者抗拒疟疾疫苗的主要原因。

结论

本研究结果为照顾者对疟疾疫苗的知识提供了有价值的见解,突出了影响疟疾疫苗接受度的因素。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4f86/11091434/b0b74ff506d0/cevr-13-121-g001.jpg

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