The Pediatric Research in Emergency Therapeutics (PRETx) Program, Division of Emergency Medicine, Department of Pediatrics, University of British Columbia, and BC Children's Hospital Research Institute, Vancouver, BC, Canada.
The Pediatric Research in Emergency Therapeutics (PRETx) Program, Division of Emergency Medicine, Department of Pediatrics, University of British Columbia, and BC Children's Hospital Research Institute, Vancouver, BC, Canada.
Vaccine. 2020 Nov 10;38(48):7668-7673. doi: 10.1016/j.vaccine.2020.09.084. Epub 2020 Oct 10.
More than 100 COVID-19 vaccine candidates are in development since the SARS-CoV-2 genetic sequence was published in January 2020. The uptake of a COVID-19 vaccine among children will be instrumental in limiting the spread of the disease as herd immunity may require vaccine coverage of up to 80% of the population. Prior history of pandemic vaccine coverage was as low as 40% among children in the United States during the 2009 H1N1 influenza pandemic.
To investigate predictors associated with global caregivers' intent to vaccinate their children against COVID-19, when the vaccine becomes available.
An international cross sectional survey of 1541 caregivers arriving with their children to 16 pediatric Emergency Departments (ED) across six countries from March 26 to May 31, 2020.
65% (n = 1005) of caregivers reported that they intend to vaccinate their child against COVID-19, once a vaccine is available. A univariate and subsequent multivariate analysis found that increased intended uptake was associated with children that were older, children with no chronic illness, when fathers completed the survey, children up-to-date on their vaccination schedule, recent history of vaccination against influenza, and caregivers concerned their child had COVID-19 at the time of survey completion in the ED. The most common reason reported by caregivers intending to vaccinate was to protect their child (62%), and the most common reason reported by caregivers refusing vaccination was the vaccine's novelty (52%).
The majority of caregivers intend to vaccinate their children against COVID-19, though uptake will likely be associated with specific factors such as child and caregiver demographics and vaccination history. Public health strategies need to address barriers to uptake by providing evidence about an upcoming COVID-19 vaccine's safety and efficacy, highlighting the risks and consequences of infection in children, and educating caregivers on the role of vaccination.
自 2020 年 1 月公布 SARS-CoV-2 基因序列以来，已有超过 100 种 COVID-19 疫苗候选物正在开发中。由于群体免疫可能需要高达 80%的人口接种疫苗，因此在儿童中接种 COVID-19 疫苗对于限制疾病传播至关重要。在美国，2009 年 H1N1 流感大流行期间，儿童的大流行疫苗接种率低至 40%。
调查与全球照顾者在 COVID-19 疫苗可用时为其子女接种疫苗的意愿相关的预测因素。
这是一项于 2020 年 3 月 26 日至 5 月 31 日期间在六个国家的 16 个儿科急诊部门对 1541 名带着孩子就诊的照顾者进行的国际横断面调查。
65%（n=1005）的照顾者报告说，一旦有疫苗可用，他们打算为孩子接种 COVID-19 疫苗。单变量和随后的多变量分析发现，接种意愿增加与年龄较大的儿童、无慢性病的儿童、父亲完成调查、疫苗接种计划及时的儿童、最近接种流感疫苗的历史以及在 ED 完成调查时担心孩子患有 COVID-19 的照顾者有关。打算接种疫苗的照顾者报告的最常见原因是保护孩子（62%），而拒绝接种疫苗的照顾者报告的最常见原因是疫苗的新颖性（52%）。
大多数照顾者打算为孩子接种 COVID-19 疫苗，但接种率可能与儿童和照顾者的人口统计学特征和疫苗接种史等特定因素有关。公共卫生策略需要解决接种疫苗的障碍，提供有关即将推出的 COVID-19 疫苗的安全性和有效性的证据，强调儿童感染的风险和后果，并教育照顾者接种疫苗的作用。
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