Wang Jiaying, Ma Zihui, Wang Chengtao, Chen Wei
Key Laboratory of Geriatric Nutrition and Health, Ministry of Education, Beijing Advanced Innovation Center for Food Nutrition and Human Health, Beijing Engineering and Technology Research Center of Food Additives, School of Food and Health, Beijing Technology and Business University, Beijing, 100048 People's Republic of China.
Food Sci Biotechnol. 2024 Mar 8;33(8):1751-1758. doi: 10.1007/s10068-024-01542-y. eCollection 2024 Jun.
(), a nutritious fungus and traditional medicinal resource, is known for melanin. This review aims to summarize the research progress on melanin in , specifically focusing on biosynthesis, fermentation production, extraction processes, physicochemical characterization, biological functions, and applications. The biosynthesis of melanin in primarily involves the oxidative polymerization reaction of phenolic compounds. To enhance melanin production, strategies such as deep fermentation culture, selection of optimal fermentation materials, and optimization of the culture medium have been employed. Various extraction processes have been compared to determine their impact on the physicochemical properties and stability of melanin. Moreover, the antioxidant and antibiofilm activities of melanin, as well as its potential beneficial effects on the human body through in vivo experiments, have been investigated. These findings provide valuable insights into the application of melanin and serve as a reference for future research in this field.
（）是一种营养丰富的真菌和传统药用资源，以黑色素而闻名。本综述旨在总结关于（）中黑色素的研究进展，特别关注其生物合成、发酵生产、提取工艺、物理化学特性、生物学功能及应用。（）中黑色素的生物合成主要涉及酚类化合物的氧化聚合反应。为提高黑色素产量，已采用深层发酵培养、选择最佳发酵原料和优化培养基等策略。已比较了各种提取工艺以确定它们对黑色素物理化学性质和稳定性的影响。此外，还研究了（）黑色素的抗氧化和抗生物膜活性，以及通过体内实验对人体的潜在有益作用。这些发现为（）黑色素的应用提供了有价值的见解，并为该领域的未来研究提供参考。
