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人乳库现行最佳实践综述。

Review of current best practices for human milk banking.

机构信息

Department of Pediatrics, Sinai Health, Toronto, Ontario, Canada.

Department of Nutritional Sciences, University of Toronto, Toronto, Ontario, Canada.

出版信息

Matern Child Nutr. 2024 Jun;20 Suppl 4(Suppl 4):e13657. doi: 10.1111/mcn.13657. Epub 2024 May 16.

Abstract

Mother's/parent milk is the optimal way to feed infants and when unavailable, supplemental donor human milk is preferred. A safe supply of donor human milk should be available for all low birthweight infants for whom it has been shown to reduce morbidity. Human milk banking has been in existence for more than a century, although largely shut down during the 1980s, primarily due to fears of human immunodeficiency virus transmission. With renewed security in milk banking, has come an exponential growth in human donor milk use. Guidelines for milk banking have been published in many countries including Australia, France, India, Italy, Spain, Switzerland, the United Kingdom and the nonprofit organization PATH. The European Milk Bank Association and the Human Milk Banking Association of North America have also published recommendations for milk banks throughout Europe and North America, respectively. Although there is variability among these guidelines, there is general consensus on quality control measures required to provide a supply of safe donor milk. These measures include effective donor screening, safe collection, transport and storage of milk, standardized pasteurization and bacteriological testing. Operational considerations are also critical, such as appropriate training for staff, equipment maintenance and cleaning, protocol and record keeping and inspection and accreditation. Clearly delineating these key quality control measures provides an excellent foundation for establishing international guidelines. Acceptable modifications must be established for low- and middle-income countries that do not have sufficient resources; overly burdensome guidelines may make establishing a milk bank unnecessarily prohibitive. This review presents a summary of current best practices for human milk banking.

摘要

母乳是喂养婴儿的最佳方式,在无法获得母乳的情况下,应优先选择补充捐赠人母乳。应为所有低出生体重儿提供安全的捐赠人母乳供应,因为已证明这可以降低发病率。人乳库已经存在了一个多世纪,尽管在 20 世纪 80 年代基本关闭,主要是由于对人类免疫缺陷病毒传播的担忧。随着对人乳库安全性的重新认识,人乳捐赠的使用呈指数级增长。包括澳大利亚、法国、印度、意大利、西班牙、瑞士、英国和非营利组织 PATH 在内的许多国家都发布了人乳库指南。欧洲母乳库协会和北美人乳库协会也分别为欧洲和北美各地的人乳库发布了建议。尽管这些指南存在差异,但在提供安全的捐赠人母乳供应所需的质量控制措施方面存在普遍共识。这些措施包括有效的供体筛查、安全的母乳收集、运输和储存、标准化巴氏消毒和细菌学检测。操作注意事项也至关重要,例如为员工提供适当的培训、设备维护和清洁、协议和记录保存以及检查和认证。明确划定这些关键的质量控制措施为制定国际准则提供了良好的基础。对于资源不足的低收入和中等收入国家,必须建立可接受的修改;过于繁琐的准则可能会使建立母乳库变得不必要地禁止。这篇综述介绍了人乳库的当前最佳实践。

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