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有效改善妊娠纹的方法:一种利用聚-DL-乳酸的激光微射流注射器的新方法。

Effective improvement methods for striae distensae: A novel approach utilizing laser-induced micro-jet injectors with poly-d,l-lactic acid.

机构信息

SeoAhSong Dermatologic Clinic, Seoul, Korea.

Department of Oral Biology, Division in Anatomy and Developmental Biology, Human Identification Research Institute, BK21 FOUR Project, Yonsei University College of Dentistry, Seoul, Korea.

出版信息

J Cosmet Dermatol. 2024 Sep;23(9):2876-2881. doi: 10.1111/jocd.16366. Epub 2024 May 16.

Abstract

INTRODUCTION

Striae distensae (SD), or stretch marks, result from rapid stretching of the skin due to various factors. Conventional treatments often yield unsatisfactory results, leading to the exploration of alternative methods. Laser-induced microjet technology offers a promising approach for drug delivery to target areas. This study investigates the efficacy of using a microjet injector with poly-d,l-lactic acid for treating SD.

METHODS

Four female participants with SD were treated with poly-d,l-lactic acid solution using a microjet injector over five sessions. Patients were assessed based on severity scales before and after treatment. Topical anesthetics were applied to minimize discomfort. Injection techniques were optimized to reduce side effects such as bleeding and pain.

RESULTS

All patients showed significant improvement in SD appearance after 5-7 treatments. Assessment scales indicated positive outcomes both immediately after treatment and at the 32-week follow-up. Minimal side effects, primarily petechiae, were observed.

DISCUSSION

Laser-induced microjet technology offers several advantages, including rapid drug delivery and mechanotransduction effects, promoting skin regeneration. Poly-d,l-lactic acid injections demonstrated effectiveness in treating SD, particularly when delivered via microjet injectors. Patients expressed high satisfaction due to the procedure's minimal invasiveness and quick recovery.

CONCLUSION

Utilizing a needleless microjet injector with poly-d,l-lactic acid shows promise as a treatment for SD, typically requiring 5-7 sessions for optimal results. Mild petechiae may occur as a common side effect. This approach offers an effective and minimally invasive alternative for addressing this common cosmetic concern.

摘要

简介

妊娠纹(SD)是由于各种因素导致皮肤快速拉伸而产生的。传统的治疗方法往往效果不佳,因此需要探索替代方法。激光微喷射技术为药物输送到目标区域提供了一种很有前途的方法。本研究探讨了使用微喷射注射器和聚-DL-乳酸治疗 SD 的疗效。

方法

四名患有 SD 的女性患者接受了五次微喷射注射器聚-DL-乳酸溶液治疗。患者在治疗前后根据严重程度量表进行评估。应用局部麻醉剂以减轻不适。优化注射技术以减少出血和疼痛等副作用。

结果

所有患者在 5-7 次治疗后 SD 外观均有明显改善。评估量表显示治疗后即刻和 32 周随访时均有积极的结果。仅观察到轻微的副作用,主要是瘀点。

讨论

激光诱导微喷射技术具有快速药物输送和机械转导效应等优点,可促进皮肤再生。聚-DL-乳酸注射在治疗 SD 方面显示出有效性,特别是通过微喷射注射器给药时。由于该程序的微创性和快速恢复,患者表示非常满意。

结论

使用无针微喷射注射器和聚-DL-乳酸治疗 SD 具有良好的效果,通常需要 5-7 次治疗才能达到最佳效果。常见的副作用是轻微的瘀点。这种方法为解决常见的美容问题提供了一种有效且微创的替代方法。

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