Friedland G H, Harris C, Butkus-Small C, Shine D, Moll B, Darrow W, Klein R S
Arch Intern Med. 1985 Aug;145(8):1413-7.
We studied the demographic characteristics, drug use patterns, and sexual habits of intravenous (IV) drug abusers to further define this population at risk for acquired immunodeficiency syndrome (AIDS). Sixteen IV drug abuser patients with AIDS, 24 IV drug abuser patients with AIDS-related complex (ARC), and 14 IV drug abuser controls without evidence of AIDS or ARC were evaluated. The subjects in each group were similar demographically, in drug use practice, and in sexual orientation and experience. Of the AIDS and ARC patients, 34 (88%) of 40, including all seven homosexual men, shared needles, as did all drug abusers without AIDS or ARC. Seventy-four percent of patients, including all homosexual men, attended "shooting galleries," where anonymous multiple-partner needle sharing took place. Needle sharing supports the hypothesis of AIDS transmission by a blood-borne route, can explain the spread of AIDS and the high rate of seropositivity to the putative AIDS agent among IV drug abusers, and is a logical link between IV drug abusers and male homosexuals, the two largest groups with AIDS.
我们研究了静脉注射吸毒者的人口统计学特征、用药模式和性行为习惯，以进一步明确这一获得性免疫缺陷综合征（艾滋病）高危人群。对16例患艾滋病的静脉注射吸毒者、24例患艾滋病相关综合征（ARC）的静脉注射吸毒者以及14例无艾滋病或ARC证据的静脉注射吸毒者对照进行了评估。每组受试者在人口统计学、用药习惯、性取向和性经历方面相似。在40例艾滋病和ARC患者中，有34例（88%），包括所有7名同性恋男性，共用针头，无艾滋病或ARC的吸毒者也都如此。74%的患者，包括所有同性恋男性，去过“射击馆”，在那里存在匿名的多性伴共用针头情况。共用针头支持了艾滋病通过血液传播途径传播的假说，能够解释艾滋病的传播以及静脉注射吸毒者中假定艾滋病病原体血清阳性率高的现象，并且是静脉注射吸毒者和男性同性恋者（艾滋病患者最多的两个群体）之间的合理关联。
