B 细胞慢性淋巴细胞白血病中的 14;19 易位：一种新的复发性染色体畸变。
A 14;19 translocation in B-cell chronic lymphocytic leukemia: a new recurring chromosome aberration.
作者信息
Ueshima Y, Bird M L, Vardiman J W, Rowley J D
出版信息
Int J Cancer. 1985 Sep 15;36(3):287-90.
PMID:3875568
Abstract
Four of 30 patients with a diagnosis of B-CLL or prolymphocytic transformation of CLL, who had an adequate cytogenetic analysis, had abnormalities involving 14q32. Three of the 4 had a translocation involving chr. 19; in 2 of them it appeared to be t(14;19) (q32;q13.1). The third patient probably had the same translocation. All 3 patients had received therapy prior to cytogenetic analysis.
摘要
30例诊断为B细胞慢性淋巴细胞白血病（B-CLL）或慢性淋巴细胞白血病（CLL）幼淋巴细胞转化且进行了充分细胞遗传学分析的患者中，有4例存在涉及14q32的异常。这4例中的3例有涉及19号染色体的易位；其中2例似乎是t(14;19) (q32;q13.1)。第3例患者可能有相同的易位。所有3例患者在进行细胞遗传学分析之前均接受过治疗。
Zotero 插件