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Purification and immunochemical properties of Escherichia coli B polysaccharide cross-reacting with Salmonella typhi Vi antigen: preliminary evidence for cross-reaction of the polysaccharide with Escherichia coli K1 antigen.与伤寒沙门氏菌Vi抗原发生交叉反应的大肠杆菌B多糖的纯化及免疫化学特性：该多糖与大肠杆菌K1抗原发生交叉反应的初步证据
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本文引用的文献

1
Protein measurement with the Folin phenol reagent.使用福林酚试剂进行蛋白质测定。
J Biol Chem. 1951 Nov;193(1):265-75.
2
The properties of bovine serum albumin and chymotrypsinogen A in solvent mixtures containing phenol.在含有苯酚的溶剂混合物中牛血清白蛋白和α-胰凝乳蛋白酶原A的性质
Biochem J. 1966 Nov;101(2):265-73. doi: 10.1042/bj1010265.
3
[On the common determinants of Enterobacteriaceae].[关于肠杆菌科的共同决定因素]
Pathol Microbiol (Basel). 1968;31(6):321-7.
4
The surface antigens and phage receptors in Escherichia coli B.
Proc Soc Exp Biol Med. 1968 Jun;128(2):434-8. doi: 10.3181/00379727-128-33031.
5
Reaginic antibody production to protein antigens of Escherichia coli and Pseudomonas aeruginosa by mice.小鼠针对大肠杆菌和铜绿假单胞菌蛋白质抗原产生反应素抗体。
Infect Immun. 1976 Sep;14(3):694-702. doi: 10.1128/iai.14.3.694-702.1976.
6
Immunological studies of an antigen common to many gram-negative bacteria with special reference to E. coli. Characterization and biological significance.
Int Arch Allergy Appl Immunol. 1975;48(1):72-81. doi: 10.1159/000231293.

对大肠杆菌B表面抗原的免疫反应。

Immune response to Escherichia coli B surface antigens.

作者信息

Taplits M, Michael J G

出版信息

Infect Immun. 1979 Sep;25(3):943-5. doi: 10.1128/iai.25.3.943-945.1979.

DOI:10.1128/iai.25.3.943-945.1979
PMID:387598
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC414538/
Abstract

The cell surface antigens of Escherichia coli B were investigated. We found that mice immunized with live bacteria responded with an immune response directed mainly against the protein structure of the cell surface. The lipopolysaccharide component of the bacterium was immunogenic, but its contribution to the overall response was only secondary. It is suggested that when considering the immune response to gram-negative bacteria, more attention should be given to the protein antigens.

摘要

对大肠杆菌B的细胞表面抗原进行了研究。我们发现，用活细菌免疫的小鼠产生的免疫反应主要针对细胞表面的蛋白质结构。该细菌的脂多糖成分具有免疫原性，但其对整体反应的贡献仅为次要。建议在考虑对革兰氏阴性菌的免疫反应时，应更多关注蛋白质抗原。