对大肠杆菌B表面抗原的免疫反应。
Immune response to Escherichia coli B surface antigens.
作者信息
Taplits M, Michael J G
出版信息
Infect Immun. 1979 Sep;25(3):943-5. doi: 10.1128/iai.25.3.943-945.1979.
Abstract
The cell surface antigens of Escherichia coli B were investigated. We found that mice immunized with live bacteria responded with an immune response directed mainly against the protein structure of the cell surface. The lipopolysaccharide component of the bacterium was immunogenic, but its contribution to the overall response was only secondary. It is suggested that when considering the immune response to gram-negative bacteria, more attention should be given to the protein antigens.
摘要
对大肠杆菌B的细胞表面抗原进行了研究。我们发现，用活细菌免疫的小鼠产生的免疫反应主要针对细胞表面的蛋白质结构。该细菌的脂多糖成分具有免疫原性，但其对整体反应的贡献仅为次要。建议在考虑对革兰氏阴性菌的免疫反应时，应更多关注蛋白质抗原。
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