Barts Health NHS Trust, London, UK
Barts NHS Health Trust, London, UK.
Clin Med (Lond). 2023 Jul;23(4):284-291. doi: 10.7861/clinmed.2023-0168.
Obesity research is advancing swiftly, but the increase in obesity prevalence is faster. Over the past three decades, researchers have found that biopsychosocial factors determine weight gain much more than personal choices and responsibility. Various genes have found to predispose people to obesity by interacting with our obesogenic environment. In this review, we discuss the impact of physical inactivity, excessive caloric intake, intrauterine environment, postnatal influences, insufficient sleep, drugs, medical conditions, socioeconomic status, ethnicity, psychosocial stress, endocrine disrupting chemicals and the gastrointestinal microbiome, on the occurrence of obesity.
肥胖研究正在迅速推进，但肥胖症的患病率增长得更快。在过去的三十年中，研究人员发现，生物心理社会因素决定体重增加的程度远超过个人选择和责任。各种基因已被发现通过与我们的肥胖环境相互作用而使人易患肥胖症。在这篇综述中，我们讨论了身体活动不足、卡路里摄入过多、宫内环境、产后影响、睡眠不足、药物、疾病、社会经济地位、种族、心理社会压力、内分泌干扰化学物质和胃肠道微生物组对肥胖发生的影响。
