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去酪氨酸γ-内啡肽与HLA I类分子之间的相互作用:一种HLA - A2亚型的血清学检测

Interaction between des-Tyr1-gamma-endorphin and HLA class I molecules: serological detection of an HLA-A2 subtype.

作者信息

Claas F H, van der Poel J J, Castelli-Visser R, Pool J, Chen R B, Xu K Y, van Rood J J

出版信息

Immunogenetics. 1985;22(4):309-14. doi: 10.1007/BF00430914.

DOI:10.1007/BF00430914
PMID:3876989
Abstract

Preincubation of lymphocytes with des-Tyr1-gamma-endorphin (DT gamma E) inhibits the reaction between some HLA alloantisera and their corresponding antigens. One HLA-A2-specific antiserum was found which could detect a subtype of the HLA-A2 antigen on DT gamma E-treated lymphocytes from some donors. Comparison with the HLA-A2 subtypes as defined by a combination of cytotoxic T lymphocyte typing and biochemistry showed a complete correlation with the previously described HLA-A2.3 subtype.

摘要

淋巴细胞与去酪氨酸γ-内啡肽(DTγE)预孵育可抑制某些HLA同种异体抗血清与其相应抗原之间的反应。发现一种HLA - A2特异性抗血清,它能够在来自一些供体的经DTγE处理的淋巴细胞上检测到HLA - A2抗原的一个亚型。通过细胞毒性T淋巴细胞分型和生物化学相结合所定义的HLA - A2亚型进行比较,结果显示与先前描述的HLA - A2.3亚型完全相关。

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本文引用的文献

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Identification of human CML target. HLA-B locus (B12) antigen variants defined by CTL generated between B locus-identical (B12) responder-stimulator pairs.人类慢性粒细胞白血病靶点的鉴定。由B位点相同(B12)的反应者-刺激者对之间产生的细胞毒性T淋巴细胞所定义的HLA-B位点(B12)抗原变体。
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2
Biochemical analysis of variant HLA-B27 antigens.变异型HLA - B27抗原的生化分析
Hum Immunol. 1983 Feb;6(2):111-7. doi: 10.1016/0198-8859(83)90067-8.
3
Definition of four HLA-A2 subtypes by CML typing and biochemical analysis.通过慢性粒细胞白血病分型和生化分析对四种HLA - A2亚型进行定义。
采用PCR-SSOP-Luminex方法对日本人群HLA-A、-B、-C和-DRB1基因座进行高通量DNA分型。
Immunogenetics. 2005 Nov;57(10):717-29. doi: 10.1007/s00251-005-0048-3. Epub 2005 Nov 8.
Immunogenetics. 1983;17(6):609-21. doi: 10.1007/BF00366129.
4
Comparison of one-dimensional IEF patterns for serologically detectable HLA-A and B allotypes.血清学可检测的HLA - A和B同种异型的一维等电聚焦图谱比较。
Immunogenetics. 1984;19(3):217-31. doi: 10.1007/BF00364765.
5
The monoclonal antibody CR11-351 discriminates HLA-A2 variants identified by T cells.单克隆抗体CR11-351可区分由T细胞识别的HLA-A2变体。
Immunogenetics. 1983;18(1):23-35. doi: 10.1007/BF00401353.
6
Differential recognition of the serologically defined HLA-A2 antigen by allogeneic cytotoxic T cells. II. Definition of three HLA-A2 subtypes by CTLs.同种异体细胞毒性T细胞对血清学定义的HLA - A2抗原的差异识别。II. 细胞毒性T淋巴细胞对三种HLA - A2亚型的定义。
Immunogenetics. 1983;17(6):599-608. doi: 10.1007/BF00366128.
7
Hla, and the response to treatment with gamma-type endorphins in schizophrenia.
J Immunogenet. 1982 Dec;9(6):381-8. doi: 10.1111/j.1744-313x.1982.tb00999.x.
8
Subtypes of HLA-B27 detected by cytotoxic T lymphocytes and their role in self-recognition.细胞毒性T淋巴细胞检测到的HLA - B27亚型及其在自我识别中的作用。
Hum Immunol. 1982 Dec;5(4):259-68. doi: 10.1016/0198-8859(82)90018-0.
9
Differential recognition of the serologically defined HLA-A2 antigen by allogeneic cytotoxic T cells. I. Population studies.同种异体细胞毒性T细胞对血清学定义的HLA - A2抗原的差异识别。I. 群体研究。
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