Tohidi Nafe Melika, Movahedi Ariyo, Djazayery Abolghasem
Department of Nutrition, Science and Research Branch, Islamic Azad University, Tehran, Iran.
Front Nutr. 2024 May 6;11:1370562. doi: 10.3389/fnut.2024.1370562. eCollection 2024.
Diseases and disorders related to mental health are spreading like other chronic diseases all around the world. Considering the role of food in the prevention and treatment of these disorders, including major depression, investigating the relationship between different food patterns and this disorder is of particular importance. The aim of this study was to compare Dutch healthy eating and healthy eating indexes and anthropometry in patients with major depression with healthy individuals.
In this case-control study, the final analysis was performed on 67 men and 111 women with an age range of 20-30 years. Height (cm), weight (kg), food frequency questionnaire (FFQ), physical activity (MET-min/week), demographic and PHQ-9 questionnaires were taken from all participants. In the following, all the food ingredients and their components were extracted and used to calculate HEI-2015 and DHD. Statistical analysis was performed using SPSS software with independent -test, logistic regression and chi-square.
It was found that people with major depression in this study were mostly women and occupied. The average HEI-2015 in healthy people and those with major depression was 58 and 54.3, respectively. Also, the average DHD in these people was 60.5 and 55, respectively. HEI-2015 and DHD had a significant negative correlation with depression score ( = -0.16, -value = 0.03) ( = -0.19, -value = 0.01). Also, in the logistic regression model, before and even after adjusting confounders, HEI-2015 and DHD had a reduced odds ratio in people suffering from major depression. The two groups did not differ significantly in terms of the average factors of height, weight and body mass index (BMI).
It seems that HEI2015 and DHD have a significant relationship in reducing major depression. However, due to the small number of studies in this regard, especially in the field of DHD, the need for more studies seems necessary.
与心理健康相关的疾病和失调正在像其他慢性病一样在全球蔓延。考虑到食物在预防和治疗这些失调（包括重度抑郁症）中的作用，研究不同饮食模式与这种失调之间的关系尤为重要。本研究的目的是比较重度抑郁症患者与健康个体的荷兰健康饮食和健康饮食指数以及人体测量学指标。
在这项病例对照研究中，对年龄在20 - 30岁的67名男性和111名女性进行了最终分析。从所有参与者处获取身高（厘米）、体重（千克）、食物频率问卷（FFQ）、身体活动（代谢当量 - 分钟/周）、人口统计学和PHQ - 9问卷。接下来，提取所有食物成分及其组成部分，用于计算2015年健康饮食指数（HEI - 2015）和荷兰健康饮食（DHD）。使用SPSS软件进行统计分析，采用独立样本t检验、逻辑回归和卡方检验。
研究发现，本研究中的重度抑郁症患者大多为女性且有工作。健康人群和重度抑郁症患者的平均HEI - 2015分别为58和54.3。此外，这些人群的平均DHD分别为60.5和55。HEI - 2015和DHD与抑郁评分呈显著负相关（r = -0.16，p值 = 0.03）（r = -0.19，p值 = 0.01）。同样，在逻辑回归模型中，在调整混杂因素之前甚至之后，HEI - 2015和DHD在重度抑郁症患者中的比值比均降低。两组在身高、体重和体重指数（BMI）的平均因素方面无显著差异。
似乎HEI2015和DHD在减轻重度抑郁症方面存在显著关系。然而，由于这方面的研究数量较少，尤其是在DHD领域，似乎有必要进行更多研究。
