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饮食模式与成年女性重度抑郁症的相关性:病例对照研究。

Association between Dietary Patterns and Major Depression in Adult Females: A Case-Control Study.

机构信息

Social Determinants of Health Research Center, Urmia University of Medical Sciences, Urmia, Iran.

Clinical Research Development Unit of Imam Khomeini Hospital, Urmia University of Medical Sciences, Urmia, Iran.

出版信息

J Res Health Sci. 2021 Jan 12;21(1):e00506. doi: 10.34172/jrhs.2021.37.

Abstract

BACKGROUND

Depression is one of the most common mental disorders. This study aimed to determine the association between dietary patterns and major depression in adult females.

STUDY DESIGN

A case-control study. .

METHODS

This study was conducted on adult females suffering from major depression within the age range from 19 to 65 years. The total participants of this study included 170 cases and 340 controls. Dietary intakes were collected using a 168-item validated semi-quantitative food-frequency questionnaire. Household food security was measured using a locally adapted Household Food Insecurity Access Scale. Moreover, the depression status of the adult females was assessed through a validated "Beck" questionnaire. Logistic regression was utilized to assess the association between dietary pattern scores and depression.

RESULTS

The mean ±SD ages of the participants were 36.97 ±11.28 and 36.07 ±10.58 years in the case and control groups, respectively (P=0.374), and five major dietary patterns were extracted in this study. The odds ratio (OR) in the last adjusted model was (OR: 0.61; 95% CI: 0.46, 0.81); therefore, the "Healthy pattern" was significantly inversely associated with the odds of depression. Adherence to the "Western pattern" significantly increased depression by 29% (OR: 1.29; 95% CI: 1.06, 1.59). Furthermore, the "Traditional pattern" was positively associated with depression (OR: 1.16; 95% CI: 0.94, 1.43). There was no significant association between "Sugar and fast food" and "red meat and oils" dietary pattern and depression.

CONCLUSION

Healthy dietary pattern reduces the risk of depression in adult females; however, the western and traditional dietary patterns increases this risk.

摘要

背景

抑郁症是最常见的精神障碍之一。本研究旨在确定成年人女性的饮食模式与重度抑郁症之间的关联。

研究设计

病例对照研究。

方法

本研究纳入了年龄在 19 至 65 岁之间患有重度抑郁症的成年女性患者。本研究的总参与者包括 170 例病例和 340 例对照。采用经过验证的 168 项半定量食物频率问卷收集饮食摄入量。家庭粮食保障情况采用经过本地化改编的家庭粮食不安全获取量表进行衡量。此外,采用经过验证的“贝克”问卷评估成年女性的抑郁状况。采用逻辑回归评估饮食模式评分与抑郁之间的关联。

结果

病例组和对照组参与者的平均年龄分别为 36.97±11.28 岁和 36.07±10.58 岁(P=0.374),本研究共提取了 5 种主要的饮食模式。最后调整模型中的比值比(OR)为(OR:0.61;95%CI:0.46,0.81);因此,“健康模式”与抑郁的几率呈显著负相关。遵循“西方模式”会使抑郁的几率显著增加 29%(OR:1.29;95%CI:1.06,1.59)。此外,“传统模式”与抑郁呈正相关(OR:1.16;95%CI:0.94,1.43)。“糖和快餐”以及“红肉和油”饮食模式与抑郁之间无显著关联。

结论

健康的饮食模式可降低成年女性患抑郁症的风险;然而,西方和传统的饮食模式会增加这种风险。

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