Zhang Qinghe, Yan Ke, Zheng Xiaoqin, Liu Qiuping, Han Yi, Liu Zuguo
Department of Ophthalmology, The First Affiliated Hospital of University of South China, Hengyang Medical School, University of South China, Hengyang Hunan 421001, China.
Xiamen University Affiliated Xiamen Eye Center, Fujian Provincial Key Laboratory of Ophthalmology and Visual Science, Fujian Engineering and Research Center of Eye Regenerative Medicine, Eye Institute of Xiamen University, School of Medicine, Xiamen University, Xiamen Fujian 361005, China.
Mater Today Bio. 2024 May 6;26:101082. doi: 10.1016/j.mtbio.2024.101082. eCollection 2024 Jun.
Hydrogel presents a three-dimensional polymer network with high water content. Over the past decade, hydrogel has developed from static material to intelligent material with controllable response. Various stimuli are involved in the formation of hydrogel network, among which photo-stimulation has attracted wide attention due to the advantages of controllable conditions, which has a good application prospect in the treatment of ophthalmic diseases. This paper reviews the application of photo-crosslink hydrogels in ophthalmology, focusing on the types of photo-crosslink hydrogels and their applications in ophthalmology, including drug delivery, tissue engineering and 3D printing. In addition, the limitations and future prospects of photo-crosslink hydrogels are also provided.
水凝胶呈现出具有高含水量的三维聚合物网络。在过去十年中，水凝胶已从静态材料发展成为具有可控响应的智能材料。各种刺激参与了水凝胶网络的形成，其中光刺激因其条件可控的优点而备受关注，在眼科疾病治疗中具有良好的应用前景。本文综述了光交联水凝胶在眼科中的应用，重点介绍了光交联水凝胶的类型及其在眼科中的应用，包括药物递送、组织工程和3D打印。此外，还阐述了光交联水凝胶的局限性和未来前景。
